Detection of breast cancer lymph node metastases in frozen sections with a point-of-care low-cost microscope scanner Low-cost point-of-care digital microscopy for frozen section analysis
Oscar Holmström, Nina Linder, Hannu Moilanen, Antti Suutala, Stig Nordling, Anders Ståhls, Mikael Lundin, Vinod Diwan, Johan Lundin, Paul J. van Diest
Abstract
In this article we evaluate a prototype of a portable, miniature digital microscope scanner for diagnostic assessment of lymph node frozen sections, obtained during breast cancer surgery. Key features of the device include support for whole slide scanning, cloud-connectivity and the use of significantly more inexpensive components, compared to conventional devices. We used the device to digitize archived sentinel lymph node frozen sections and two pathologists with experience in breast cancer histopathology assessed the whole slide images for the detection of metastases. Results were compared
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