Conserved exchange of paralog proteins during neuronal differentiation Conserved exchange of paralog proteins
Domenico Di Fraia, Mihaela Anitei, Marie-Therese Mackmull, Luca Parca, Laura Behrendt, Amparo Andres-Pons, Darren Gilmour, Manuela Helmer Citterich, Christoph Kaether, Martin Beck, Alessandro Ori
Abstract
'Luca Parca' 'Laura Behrendt' 'Amparo Andres-Pons' 'Darren Gilmour' 'Manuela Helmer Citterich' 'Christoph Kaether' 'Martin Beck' 'Alessandro Ori\u202c\u202c'] Paralog proteins promote fine tuning of protein complexes. The author identified a specific paralog signature conserved across vertebrate neuronal differentiation. Altering the ratio of SEC23 paralogs in the COPII complex influences neuronal differentiation in a opposite way.
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