A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations

Abstract

'Elizabeth A. Buffalo' 'Jordan S. Farrell' 'David J. Foster' 'Loren M. Frank' 'Tamara Gedankien' 'Jean Gotman' 'Jennifer A. Guidera' 'Kari L. Hoffman' 'Joshua Jacobs' 'Michael J. Kahana' 'Lin Li' 'Zhenrui Liao' 'Jack J. Lin' 'Attila Losonczy' 'Rafael Malach' 'Matthijs A. van der Meer' 'Kathryn McClain' 'Bruce L. McNaughton' 'Yitzhak Norman' 'Andrea Navas-Olive' 'Liset M. de la Prida' 'Jon W. Rueckemann' 'John J. Sakon' 'Ivan Skelin' 'Ivan Soltesz' 'Bernhard P. Staresina' 'Shennan A. Weiss' 'Matthew A. Wilson' 'Kareem A. Zaghloul' 'Michaël Zugaro' 'György Buzsáki'] Decades of rodent research have established the role of hippocampal sharp wave ripples (SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in humans have suggested their role in episodic and semantic memory. Yet, common standards for recording, detection, and reporting do not exist. Here, we outline the methodological challenges involved in detecting ripple events and offer practical recommendations to improve separation from other high-frequency oscillations. We argue that shared experimental, detection, and reporting standards will provide a solid foundation for future translational discovery.