Search · four archives
Search · four archives
12 papers · ranked by Valyu relevance
Théophile Sanchez, Jean Cury, Guillaume Charpiat, Flora Jay
For the past decades, simulation-based likelihood-free inference methods have enabled researchers to address numerous population genetics problems. As the richness and amount of simulated and real genetic data keep increasing, the field has a strong opportunity to tackle tasks that current methods hardly solve.…
Md Ochiuddin Miah, Umme Habiba, Md Faisal Kabir
Brain-computer interface (BCI) research has gained increasing attention in educational contexts, offering the potential to monitor and enhance students’ cognitive states. Real-time classification of students’ confusion levels using electroencephalogram (EEG) data presents a significant challenge in this domain. Since…
Devashish Tripathi, Analabha Basu
Environmental factors play a pivotal role in shaping the genetic and phenotypic diversity among organisms. Understanding the influence of the environment on a biological phenomenon is essential for deciphering the mechanisms resulting in trait differences among organisms. In this study, we present a novel approach…
Ekaterina Noskova, Viacheslav Borovitskiy
Inference of demographic histories of species and populations is one of the central problems in population genetics. It is usually stated as an optimization problem: find a model’s parameters that maximize a certain log-likelihood. This log-likelihood is often expensive to evaluate in terms of time and hardware…
Rajarshi SinhaRoy, Christian Clauß, Ivan Ivanikov, Georg Künze
Enzyme activity and stability are strongly modulated by pH, making the catalytic pH optimum (pH _opt_) a key parameter in enzyme development and biotechnological applications. Experimental determination of pH _opt_ is, however, labor-intensive and time-consuming, motivating the development of accurate computational…
Jaime Carrasco, Fulgencio Lisón, Andrés Weintraub
Traditional Species Distribution Models (SDMs) may not be appropriate when examples of one class (e.g. absence or pseudo-absences) greatly outnumber examples of the other class (e.g. presences or observations), because they tend to favor the learning of observations more frequently. We present an ensemble method called…
Sina Dabiri, Eric R. Cole, Robert E. Gross
Brain stimulation has become an important treatment option for a variety of neurological and psychiatric diseases. A key challenge in improving brain stimulation is selecting the optimal set of stimulation parameters for each patient, as parameter spaces are too large for brute-force search and their induced effects…
Eric Schulz, Maarten Speekenbrink, Andreas Krause
This tutorial introduces the reader to Gaussian process regression as a tool to model, actively explore and exploit unknown functions. Gaussian process regression is a powerful, non-parametric Bayesian approach towards regression problems that can be utilized in exploration and exploitation scenarios. This tutorial…
Lorenz Wernisch, Tristan Edwards, Antonin Berthon, Olivier Tessier-Lariviere + 20 more
In bioelectronic medicine, neuromodulation therapies induce neural signals to the brain or organs modifying their function. Stimulation devices, capable of triggering exogenous neural signals using electrical wave forms, require a complex and multi-dimensional parameter space in order to control such wave forms.…
Masaru Sasaki, Ken Takeda, Kota Abe, Masafumi Oizumi
Gromov-Wasserstein optimal transport (GWOT) has emerged as a versatile method for unsupervised alignment in various research areas, including neuroscience, drawing upon the strengths of optimal transport theory. However, the use of GWOT in various applications has been hindered by the difficulty of finding good optima…
Lucy Xia, Christy Lee, Jingyi Jessica Li
Two-dimensional (2D) embedding methods are crucial for single-cell data visualization. Popular methods such as t-SNE and UMAP are commonly used for visualizing cell clusters; however, it is well known that t-SNE and UMAP’s 2D embedding might not reliably inform the similarities among cell clusters. Motivated by this…
Hua-Dong Xiong, Li Ji-An, Marcelo G. Mattar, Robert C. Wilson
Cognitive modeling provides a formal method to articulate and test hypotheses about cognitive processes. However, accurately and reliably estimating model parameters remains challenging due to common issues in behavioral science, such as limited data, measurement noise, experimental constraints, and model complexity.…