8 papers · ranked by Valyu relevance
Jeffrey D. Walker, Paul Aparicio, Shreya Saxena, Nicholas G. Hatsopoulos + 1 more
The ability to record neural populations during natural behavior now allows us to ask whether canonical motor-cortical dynamics, defined largely in constrained reaches to static targets, also organize self-paced, feedback-rich actions that require continuous correction. We recorded sensorimotor cortex in marmosets…
Coen S. Zandvoort, Charlotte C. Wissing, Jonathan Winter, Anna Kowalczyk + 4 more
Flexible motor control requires that movements adapt to changing temporal contexts. Here, we test whether flexible timing is driven by context-dependent encoding across cortico-cerebellar circuits and how neural dynamics within these circuits enable accurate performance. To overcome the signal-to-noise limitations of…
Xinyi Cao, Chao Ye, Shengjie Ling, Ming Li + 3 more
Fiber-shaped electronic systems provide a promising platform for wearable sensing and intelligent textiles, yet the continuous processing of uncured silicone-based conductive materials remains challenging because of their low structural stability during fiber formation. Here, we develop a coaxial wet-spinning strategy…
Prince Okyere, Junheng Li, Tobias Raufeisen, Ketevan Alania + 10 more
Memory consolidation during sleep depends on the precisely timed coordination of hippocampal reactivation with cortical slow oscillations and spindles. In humans this coupling has been characterised correlationally, while causal investigations have required intracranial stimulation in restricted patient cohorts or used…
Yinuo Zhang, Yan Zhu, Xinxin Zhang, Xinke Shen + 8 more
Postoperative delirium (POD) is a common complication in older surgical patients and substantially worsens clinical outcomes, yet existing intraoperative electroencephalography (EEG) monitoring tools lack spatial and temporal specificity, creating a need for interpretable biomarkers. We prospectively analyzed…
Yichen Zhou, Tianqing Cao, Sipeng Zhu, Qiheng He + 4 more
1## Introduction Disorders of consciousness (DoC) represent a pathological condition marked by significant impairment in both the level and content of awareness, resulting from traumatic or non-traumatic brain injury. According to illness duration, DoC are categorized as acute or prolonged, with prolonged cases…
Jalaja Madhusudhanan, Anton Parinov, Charles Fieseler, Manuel Zimmer
Behavior arises from the interplay between spontaneous brain dynamics and sensory-driven responses, yet how spontaneous neural activity shapes variability in decision-making remains unclear. We leverage the tractable C. elegans nervous system to address this question. During oxygen avoidance, we observe binary…
Anda de Witte, Anouck Matthijs, Benjamin Parrell, Dante Mantini + 4 more
Aging is frequently perceived negatively due to its association with declines in brain and motor function yet not all aspects of brain function are equally affected. The cerebellum, a brain region closely linked to motor control, undergoes clear structural changes with age, but the impact of this degeneration on…