15 papers · ranked by Valyu relevance
Yaping Xu, Lulu Ding, Shigang Wu, Jue Ruan
Composite DNA letters, by merging all four DNA nucleotides in specified ratios, offer a pathway to substantially increase the logical density of DNA digital storage (DDS) systems. However, these letters are susceptible to nucleotide errors and sampling bias, leading to a high letter error rate, which complicates…
David Kracht, Steffen Schober
Background Barcode multiplexing is a key strategy for sharing the rising capacity of next-generation sequencing devices: Synthetic DNA tags, called barcodes, are attached to natural DNA fragments within the library preparation procedure. Different libraries, can individually be labeled with barcodes for a joint…
Lulu Ding, Shigang Wu, Zhihao Hou, Alun Li + 4 more
'Weihua Pan' 'Jue Ruan'] Title: ABSTRACT Error-correcting codes (ECCs) employed in the state-of-the-art DNA digital storage (DDS) systems suffer from a trade-off between error-correcting capability and the proportion of redundancy. To address this issue, in this study, we introduce soft-decision decoding approach into…
Kees Schouhamer Immink, Jos H. Weber, Tuan Thanh Nguyen, Kui Cai + 2 more
The design of low-complexity and efficient constrained codes has been a major research item for many years. This paper reports on a versatile method named concatenated constrained codes for designing efficient fixed-length constrained codes with small complexity. A concatenated constrained code comprises two (or more)…
Michael Windisch, Jakob Wassermann, Monica Leba, Olimpiu Stoicuta + 1 more
In communication technologies such as digital watermarking, wireless sensor networks (WSNs), and visual light communication (VLC), error-correcting codes are crucial. The Enhanced Hadamard Error-Correcting Code (EHC), which is based on 2D Hadamard Basis Images, is a novel error correction technique that is presented in…
Peter Michael Schwarz, Bernd Freisleben
Today's digital data storage systems typically offer advanced data recovery solutions to address the problem of catastrophic data loss, such as software-based disk sector analysis or physical-level data retrieval methods for conventional hard disk drives. However, DNA-based data storage currently relies solely on the…
Katharina Mir, Klaus Neuhaus, Martin Bossert, Steffen Schober + 1 more
'Eshel Ben-Jacob'] We consider the design and evaluation of short barcodes, with a length between six and eight nucleotides, used for parallel sequencing on platforms where substitution errors dominate. Such codes should have not only good error correction properties but also the code words should fulfil certain…
Svitlana Matsenko, Oleksiy Borysenko, Sandis Spolitis, Aleksejs Udalcovs + 6 more
'Aleksejs Udalcovs' 'Lilita Gegere' 'Aleksandr Krotov' 'Oskars Ozolins' 'Vjaceslavs Bobrovs' 'Song-Nam Hong' 'T. Aaron Gulliver'] Forward error correction (FEC) codes combined with high-order modulator formats, i.e., coded modulation (CM), are essential in optical communication networks to achieve highly efficient and…
Michael Reimsbach, John Aycock
Having content in an archive is of limited value if it cannot be read and used. As a case study of extricating information from obsolete media, making it readable once again through deep learning techniques, we examine the Cauzin Softstrip: one of the first two-dimensional bar codes, released in 1985 by Cauzin Systems…
David M. Benton, You Yang
Concurrent coding is an encoding scheme with ‘holographic’ type properties that are shown here to be robust against a significant amount of noise and signal loss. This single encoding scheme is able to correct for random errors and burst errors simultaneously, but does not rely on cyclic codes. A simple and practical…
Kevin D Volkel, Paul W Hook, Albert Keung, Winston Timp + 2 more
Most DNA storage systems remain at a scale <1 GB and can tolerate slow decoding. However, to scale to large capacities and to advance our understanding of these systems, decoders must improve their throughput, read density, and support for varying strand length, molecule type, and encoding density. Our decoder is…
Leonid V. Bystrykh, Jo-Ann L. Stanton
The diversity and scope of multiplex parallel sequencing applications is steadily increasing. Critically, multiplex parallel sequencing applications methods rely on the use of barcoded primers for sample identification, and the quality of the barcodes directly impacts the quality of the resulting sequence data.…
Jasmine Quah, Omer Sella, Thomas Heinis
DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring DNA in the life sciences. To achieve higher accuracy for previously unseen…
Seong-Joon Park, Sunghwan Kim, Jaeho Jeong, Albert No + 3 more
We choose the image file of size 548.83 KB (16 572 × 136 nt) and encode it to the output data size of 18 432 × 152 nt. [btad548-F1] shows that the output data size of 18 432 × 152 nt with 26 nt sequence primers in the prefix and 21 nt sequence primers in the suffix. The information density of the proposed method is…
Peter Michael Schwarz, Bernd Freisleben
Background DNA is a promising storage medium for high-density long-term digital data storage. Since DNA synthesis and sequencing are still relatively expensive tasks, the coding methods used to store digital data in DNA should correct errors and avoid unstable or error-prone DNA sequences. Near-optimal rateless erasure…