PPubMed7 Sep 2026
Decoding cell–cell communication in spatial transcriptomics: mechanistic insights, modeling constraints, and analytical caveats
Yuesong Wu, Haohao Su, Yuehua Cui
Cell-cell communication (CCC) is essential for maintaining tissue organization and driving biological progression, yet its inference from transcriptomic data has long been limited by the absence of spatial context. Advances in spatial transcriptomics (ST) now enable mechanistically grounded analyses of CCC by…