BbioRxiv8 Sep 2026
The microtubule-associated proteins CKAP2 and its paralog CKAP2- Like control ciliogenesis in human cells
Luiz E. da Silva, Gabriel Campolina-Silva, Jenine Afani, Clémence Belleannée + 1 more
Ciliogenesis is an evolutionarily conserved process that leads to the assembly of cilia. This process relies on microtubule-associated proteins (MAPs) to regulate axonemal microtubule dynamics. Misregulation of MAPs often leads to changes in ciliary homeostasis, contributing to numerous ciliopathies. Although CKAP2 and…