12 papers · ranked by Valyu relevance
Yuhang Wang, Weihua Chen, Linjing Song, Zhiping Xu + 6 more
With the rapid growth of data volume in sensor networks, lossy source coding systems achieve high-efficiency data compression with low distortion under limited transmission bandwidth. However, conventional compression algorithms rely on a two-stage framework with high computational complexity and frequently struggle to…
Pengxi Fu, Zhen Wang, Jianxin Guo, Yushuai Zhang + 4 more
Modern communication systems increasingly leverage multiple information streams-including channel observations, statistical models, and contextual knowledge-to enhance decoding reliability. However, the varying and often unpredictable quality of these sources poses a critical challenge: rigid combination rules fail…
Sawako Yamashiro, Misato Nomura, Nils Chapin, Sreeja Sasidharan + 5 more
Cells sense and respond to fluid shear stress. Cell surfaces are exposed to flow, yet the influence of shear stress on the behavior of plasma membrane proteins remains unclear. Here we show that extracellular flow induces the gradient distribution of cell membrane proteins with increasing concentration toward the…
Simone Carlo Surace, Jean-Pascal Pfister, Wulfram Gerstner, Johanni Brea + 1 more
'Johanni Brea' 'Francis Ouellette'] This is a PLOS Computational Biology Education paper. The idea that the brain functions so as to minimize certain costs pervades theoretical neuroscience. Because a cost function by itself does not predict how the brain finds its minima, additional assumptions about the optimization…
Varun L. Kopparthy, Niel D. Crews
We report the development of a versatile system based on oscillating-flow methodology in a thermal gradient system for nucleic acid analysis. Analysis of DNA and RNA samples were performed in the device, without additional temperature control and complexity. The technique reported in this study eliminates the need for…
Cécile Daversin-Catty, Vegard Vinje, Kent-André Mardal, Marie E. Rognes
Flow of cerebrospinal fluid (CSF) in perivascular spaces (PVS) is one of the key concepts involved in theories concerning clearance from the brain. Experimental studies have demonstrated both net and oscillatory movement of microspheres in PVS (Mestre et al. (2018), Bedussi et al. (2018)). The oscillatory particle…
Nikhil Parthasarathy, Eleanor Batty, William Falcon, Thomas Rutten + 3 more
Decoding sensory stimuli from neural signals can be used to reveal how we sense our physical environment, and is valuable for the design of brain-machine interfaces. However, existing linear techniques for neural decoding may not fully reveal or exploit the fidelity of the neural signal. Here we develop a new…
Guillaume Quétant, Yury Belousov, Vitaliy Kinakh, Slava Voloshynovskiy + 2 more
'Slava Voloshynovskiy' 'Sotiris Kotsiantis' 'Marco Piangerelli'] We present a novel information-theoretic framework, termed as TURBO, designed to systematically analyse and generalise auto-encoding methods. We start by examining the principles of information bottleneck and bottleneck-based networks in the auto-encoding…
Ganchao Wei, Daniela de Albuquerque, Miles Martinez, Shiyang Pan + 1 more
While neuroscience experiments have repeatedly demonstrated the involvement of large populations of neurons in even simple behaviors, these studies have just as often reported that the collective dynamics of neural activity are approximately low-dimensional. As a result, methods for identifying low-dimensional latent…
Artemy Kolchinsky, Brendan D. Tracey, David H. Wolpert
Information bottleneck (IB) is a technique for extracting information in one random variable X that is relevant for predicting another random variable Y. IB works by encoding X in a compressed “bottleneck” random variable M from which Y can be accurately decoded. However, finding the optimal bottleneck variable…
Chen-Hsiu Huang, Ja-Ling Wu, Jun Chen
End-to-end learned image compression codecs have notably emerged in recent years. These codecs have demonstrated superiority over conventional methods, showcasing remarkable flexibility and adaptability across diverse data domains while supporting new distortion losses. Despite challenges such as computational…
Yikai Liu, Guang Lin, Ming Chen
Molecular dynamics (MD) simulations remain the standard tool for characterizing protein conformational landscapes, but their high computational cost limits large-scale and long-timescale applications. Recent generative models, especially diffusion-based approaches, provide promising alternatives by learning equilibrium…