6 papers · ranked by Valyu relevance
John Tower
Biological information is generally thought to be subject to selection for faithful maintenance. However, accurate preservation is often combined with regulated mechanisms that generate state change. Selectively advantageous instability (SAI) is modeled here as instability that is favored because useful alternatives…
Eliezer Masliah
How transient neural representations become integrated and stable enough to function as internal neural models remains incompletely understood. Grounded in efficient coding, Bayesian and predictive frameworks, recurrent and attractor dynamics, neural state-space models, and systems neuroscience, the Principle of…
Yuesong Wu, Haohao Su, Yuehua Cui
Cell-cell communication (CCC) is essential for maintaining tissue organization and driving biological progression, yet its inference from transcriptomic data has long been limited by the absence of spatial context. Advances in spatial transcriptomics (ST) now enable mechanistically grounded analyses of CCC by…
Henrique Reis Aguiar, Matthias H. Hennig
Predictive coding is a powerful normative framework for understanding cortical computation, but it is still an open question how biologically plausible networks with local plasticity support predictive inference and representation learning. In this work we show that a recurrent excitatory-inhibitory circuit with purely…
Sergio Cabello, Panos Giannopoulos
We study the problem of searching for a target at some unknown location in $\mathbb{R}^d$ when additional information regarding the position of the target is available in the form of predictions. In our setting, predictions come as approximate distances to the target: for each point $p\in \mathbb{R}^d$ that the…
Shanti Prasad Khanal, Chitra Bahadur Budhathoki, Bhimsen Devkota, Shyam Krishna Maharjan + 1 more
Background: Evidence indicates a lack of school-based interventions targeting adolescents' health literacy. To date, no structured, theory-driven, Delphi-guided health literacy intervention has been designed for Nepalese adolescents. Objective: This study aims to report the systematic development of a context-specific…