7 papers · ranked by Valyu relevance
Safoora Masoumi, Saeid Shahraz
Background Meta-analysis is a central method for quality evidence generation. In particular, meta-analysis is gaining speedy momentum in the growing world of quantitative information. There are several software applications to process and output expected results. Open-source software applications generating such…
Károly Bósa, Paul Heinzlreiter
Background Data preparation is a fundamental aspect of data engineering, a prerequisite for later tasks such as data visualization, reporting, and training machine learning models. Despite the recurring patterns in data transformation processes, the specific steps often vary depending on the project context, data…
Parker Ladd Bremer, Oliver Fiehn, Hong-Yu Zhang
Metabolomics has advanced to an extent where it is desired to standardize and compare data across individual studies. While past work in standardization has focused on data acquisition, data processing, and data storage aspects, metabolomics databases are useless without ontology-based descriptions of biological…
Mohammed Zniber, Youssef Fatihi, Tan-Phat Huynh, Sofia Forslund
Metabolomics is an emerging field within systems biology and represents the final step in the ‘omics’ cascade (, ). As a technology-driven discipline, metabolomics utilizes advancements in analytical chemistry and computational techniques to improve data collection, analysis, and interpretation (). Key platforms in…
Joshua M. Mitchell, Yuanye Chi, Maheshwor Thapa, Zhiqiang Pang + 2 more
To standardize metabolomics data analysis and facilitate future computational developments, it is essential is have a set of well-defined templates for common data structures. Here we describe a collection of data structures involved in metabolomics data processing and illustrate how they are utilized in a…
Christian D. Powell, Hunter N. B. Moseley
Background An updated version of the mwtab Python package for programmatic access to the Metabolomics Workbench (MetabolomicsWB) data repository was released at the beginning of 2021. Along with updating the package to match the changes to MetabolomicsWB’s ‘mwTab’ file format specification and enhancing the package’s…
Gordon Grabert, Daniel Dehncke, Tushar More, Markus List + 5 more
Advances in high-throughput techniques have revolutionized the generation of molecular biology data. These developments facilitate longitudinal studies to investigate different levels of biological systems and disease-related system changes over time, for example in metabolism and gene regulation (, , ). Recent…