13 papers · ranked by Valyu relevance
Yiyang Yu
Predictive processing theories portray the brain as a hierarchical prediction engine that minimizes prediction error, yet they lack operational definitions for the structure of a "prediction," the standardized response to a prediction error, and the mechanism that maintains consistency across successive updates.…
Yanan Bai, Wanying Wang, Jiajia Duan, Xue Wang + 5 more
Introduction Since the advent of evidence-based medicine, the decision-making process in disease diagnosis and treatment has exhibited fundamental principles that align closely with the core tenets of evidence chain theory in the legal field. Based on this, this paper aims to explore the underlying logic and practical…
Nils Küchenmeister, Alex Ivliev, Dörthe Arndt, Markus Krötzsch
Combining RDF rule languages, such as N3 or SHACL Rules, with default negation is challenging. Existing methods to stratify negation often fail for RDF rules, since individual triples do not carry enough information to meaningfully restrict potential dependencies. Blank nodes in rule heads further complicate the…
Niklas Brunn, Laia C. Guitart, Kiana Farhadyar, Camila L. Fullio + 4 more
Recent advances in spatial transcriptomics and computational modeling enable the study of cellular interactions in situ. However, existing methods quantify ligand–receptor activity pairwise or between predefined cell groups, yielding overlapping signals and limited ability to summarize concurrent interactions into…
Rohan Das, Advait Deshmukh, Alexandria Leto, Zohar Naaman + 2 more
Media narratives wield tremendous power in shaping public opinion, yet computational approaches struggle to capture the nuanced storytelling structures that communication theory emphasizes as central to how meaning is constructed. Existing approaches either miss subtle narrative patterns through coarse-grained analysis…
Shanshan Zhu, Wenjin Yan, Hu Chuan-Peng
Self-referential processing is a fundamental cognitive function, and abnormalities in its neural implementation have been reported across a range of psychiatric disorders, leading to the proposal that such alterations may constitute a transdiagnostic neurobiological feature. Yet claiming transdiagnostic requires…
Devanshi Gupta, Subbareddy Maddika
Ubiquitination is a fundamental post-translational modification that orchestrates a wide range of cellular processes. This modification is executed through a cascade of enzymatic steps involving E1 activating enzymes, E2 conjugating enzymes, and E3 ligases. Among these, E2 enzymes and specific E3 ligases primarily…
Authors not listed
Elastic modulus, G, and equilibrium swelling ratio, Q, are two properties of hydrogels, which are linked by the scaling law G ∼ Q^β, where β=-1 and -9/4 in the low and high salt limit, respectively. Tuning them independently would enable the optimization of the material design for a wide variety of distinct…
Anita R. Caron, Aleix Puig-Barbe, Ellen M. Quardokus, James P. Balhoff + 11 more
Annotation of biomedical entities with widely used, well-structured ontologies and ontology-aware tools ensures data and analyses are Findable, Accessible, Interoperable, and Reusable (FAIR). Standardized terms with synonyms support lexical search, while ontology structure enables biologically meaningful grouping of…
Xiaohang Yu, William Knottenbelt
Blockchain forensics inherently involves dynamic and iterative investigations, while many existing approaches primarily model it through static inference pipelines. We propose a paradigm shift towards Agentic Blockchain Forensics (ABF), modeling forensic investigation as a sequential decision-making process. To…
Ninghan Zhong, Ahmet Ege Tanriverdi, Kaan Kale, Sriram Vishwanath
Multi-step reasoning with Chain-of-Thought (CoT) prompting remains fragile: logical errors or hallucinations in early steps silently propagate, producing confident but incorrect conclusions. This paper presents VeryTrace, a zero-shot verification-and-repair framework that formalizes natural-language reasoning traces…
Jiaqi Wu
Many comparative analyses operate on rectangular matrices whose columns represent the same variables across observations. Phylogenomic measurements, however, are attached to tree branches. Converting locus-specific trees into a common locus-by-coordinate matrix is straightforward only when loci contain the same taxa…
Andy E. Williams
Objective We introduce the Cognitive Near-Singularity (CNS) as a falsifiable phase transition in reasoning systems: the regime in which updates are globally contracting, closed under composition, and invariant to benign reparameterizations, so that heterogeneous reasoning processes converge to a common fixed point up…