15 papers · ranked by Valyu relevance
E. Mika Diamanti, Charu Bai Reddy, Sylvia Schröder, Tomaso Muzzu + 3 more
During navigation, the visual responses of neurons in primary visual cortex (V1) are modulated by the animal’s spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but largely absent in the main thalamic pathway into V1. Similar to hippocampus, spatial…
Thomas Trevelyan James Sainsbury, Giovanni Diana, Martin Patrick Meyer
Visual neurons can have their tuning properties contextually modulated by the presence of visual stimuli in the area surrounding their receptive field, especially when that stimuli contains natural features. However, stimuli presented in specific egocentric locations may have greater behavioural relevance, raising the…
Yong Liang, Gang Wen, Jie Zhang, Simin Li + 6 more
Super-resolution structured illumination microscope (SR-SIM) has been established as a powerful tool for visualizing subcellular dynamics and studying organelle interactions in live cells. However, the interfering Gaussian beams result in a limited and nonuniform field of view (FOV) which hinders its application for…
Dirk van Moorselaar, Stefan Van der Stigchel
The visual system can flexibly adjust attentional deployment to match task demands, but whether observers can proactively modulate the spatial scope of attention based on expectations about upcoming search difficulty remains unclear. According to the zoom lens model, attention can narrow or broaden its spatial extent…
Baiwei Liu, Anna C. Nobre, Freek van Ede
Covert spatial attention is associated with spatially specific modulation of neural activity as well as with directional biases in fixational eye-movements known as microsaccades. Recently, this link has been suggested to be obligatory, such that modulation of neural activity by covert spatial attention occurs only…
Kenta Temma, Ryosuke Oketani, Toshiki Kubo, Kazuki Bando + 9 more
Resolution enhancement in structured illumination microscopy is hindered when volumetric samples are observed owing to background signals from out-of-focus planes. In this study, we utilized selective plane illumination and reversibly photoswitchable fluorescent proteins to realize structured illumination within the…
Zahra M. Aghajan, Diane Villaroman, Sonja Hiller, Tyler J. Wishard + 9 more
How the human brain supports accurate navigation of a learned environment has been an active topic of research for nearly a century^1–5^. In rodents, the theta rhythm within the medial temporal lobe (MTL) has been proposed as a neural basis for fragmenting incoming information and temporally organizing experiences and…
Zongyue Cheng, Chenmao Wang, Bowen Wei, Wenbiao Gan + 2 more
Neural modulation plays a major role in delineating the circuit mechanisms and serves as the cornerstone of neural interface technologies. Among the various modulation mechanisms, ultrasound enables noninvasive label-free deep access to mammalian brain tissue. To date, most if not all ultrasonic neural modulation…
Oscar Woolnough, Kiefer J. Forseth, Patrick S. Rollo, Zachary J. Roccaforte + 1 more
Visual inputs to early visual cortex integrate with semantic, linguistic and memory inputs in higher visual cortex, in a manner that is rapid and accurate, and enables complex computations such as face recognition and word reading. This implies the existence of fundamental organizational principles that enable such…
Ken Takiyama, Hikaru Yokoyama, Naotsugu Kaneko, Kimitaka Nakazawa
How the central nervous system (CNS) controls many joints and muscles is a fundamental question in motor neuroscience and related research areas. An attractive hypothesis is the module hypothesis: the CNS controls groups of joints or muscles (i.e., spatial modules) while providing time-varying motor commands (i.e.…
Michael X Cohen
Large-scale synchronous neural activity produces electrical fields that can be measured by electrodes outside the head, and volume conduction ensures that neural sources can be measured by many electrodes. However, most data analyses in M/EEG research are univariate, meaning each electrode is considered as a separate…
Dong Chen, Kai-Jia Sun, Liang Wang, Zhanjun Zhang + 3 more
Grid cells constitute a crucial component of the “GPS” in the mammalian brain. Recent experiments revealed that grid cell activity is anchored to environmental boundaries. More specifically, these results revealed a slight yet consistent offset of 8 degrees relative to boundaries of a square environment. The causes and…
A. Llera, R. Chauvin, P. Mulders, J. Naaijen + 2 more
Functional connectivity between brain regions is modulated by cognitive states or experimental conditions. Such connectivity variations can be appreciated in covariance or correlation matrices obtained from fMRI data. A multivariate methodology that can capture fMRI connectivity maps in light of different experimental…
Davide Spalla, Alexis Dubreuil, Sophie Rosay, Remi Monasson + 1 more
The way grid cells represent space in the rodent brain has been a striking discovery, with theoret-ical implications still unclear. Differently from hippocampal place cells, which are known to encode multiple, environment-dependent spatial maps, grid cells have been widely believed to encode space through a single low…
Yanbo Lian, Anthony N. Burkitt
Experimental studies of grid cells in the Medial Entorhinal Cortex (MEC) have shown that they are selective to an array of spatial locations in the environment that form a hexagonal grid. However, place cells in the hippocampus are only selective to a single-location of the environment while granule cells in the…