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Search · four archives
8 papers · ranked by Valyu relevance
Sergio Marco Salas, Louis B. Kuemmerle, Christoffer Mattsson-Langseth, Sebastian Tismeyer + 15 more
'Sebastian Tismeyer' 'Christophe Avenel' 'Taobo Hu' 'Habib Rehman' 'Marco Grillo' 'Paulo Czarnewski' 'Saga Helgadottir' 'Katarina Tiklova' 'Axel Andersson' 'Nima Rafati' 'Maria Chatzinikolaou' 'Fabian J. Theis' 'Malte D. Luecken' 'Carolina Wählby' 'Naveed Ishaque' 'Mats Nilsson'] The Xenium In Situ platform is a new…
Hanqiu Zhao, Xiaokuang Ma, Peng Chen, Bin Liu + 8 more
'John Zhang' 'Ankit A. Desai' 'Andrea L. Frump' 'Olga Rafikova' 'Michael B. Fallon' 'Shenfeng Qiu' 'Zhiyu Dai'] Spatial transcriptomics technologies have emerged as powerful tools for understanding cellular identity and function within the natural spatial context of tissues. Traditional transcriptomics techniques, such…
Mariia Bilous, Daria Buszta, Jonathan Bac, Senbai Kang + 8 more
Spatial transcriptomics enables high-resolution gene expression mapping in intact tissues. Xenium is widely adopted for its reliability, accessibility and data quality, yet the properties and limitations of Xenium-derived data remain poorly characterized. Here we present one of the most comprehensive Xenium datasets so…
Da Hyun Kang, Yoonjoo Kim, Ji Hyeon Lee, Hyeong Seok Kang + 2 more
Title: Simple Summary Spatial transcriptomics (ST) is an innovative technology that maps gene expression while preserving tissue structure, offering new perspectives on disease mechanisms in the lung. This review explores how ST has advanced our understanding of lung cancer and other pulmonary diseases. In lung cancer…
Hyun Ju Lim, Ye Wang, Anton Buzdin, Xinmin Li
Spatial transcriptomics technology enables the mapping of gene expression within tissues, allowing researchers to visualize the spatial distribution of RNA molecules and gain insights into cellular organization, interactions, and functions in their native environments. A variety of spatial technologies are now…
Yiming Li, Cenfu Wei, Wenjing Yang, Hai Wang + 16 more
Using over 100 intestinal tissue sections from non-diseased controls and patients with ulcerative colitis or Crohn’s disease across multiple inflammatory bowel disease consortia, we construct a spatially resolved atlas containing over three million cells and systematically evaluate two imaging-based spatial…
Hongyu Zheng, Hirak Sarkar, Benjamin J. Raphael
Spatially resolved transcriptomics (SRT) technologies measure gene expression across thousands of spatial locations within a tissue slice. Multiple SRT technologies are currently available and others are in active development, with each technology having varying spatial resolution (subcellular, single-cell, or…
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Desorption Electrospray Ionization Mass Spectrometry Imaging (DESI-MSI) is a powerful technique for molecular analysis of surfaces; however, its application of single cell studies has not been previously published. In the current work, a commercial DESI setup (DESI XS) coupled to a mass spectrometer was used to analyze…