29 papers · ranked by Valyu relevance
Brandon S Coventry, Edward L Bartlett
Typical statistical practices in the biological sciences have been increasingly called into question due to difficulties in replication of an increasing number of studies, many of which are confounded by the relative difficulty of null significance hypothesis testing designs and interpretation of p-values. Bayesian…
Gustavo A. Ballen
The fossil record is both incomplete and subject to a number of biases with different sources (e.g., preservational, statistical), which hinders making inferences about the past of life on earth. Stratigraphic intervals allow estimate two important quantities from the fossil record of a given lineage, its origination…
Carolina Luque, Juan José Sánchez Sosa
In this manuscript, we discuss the substantial importance of Bayesian reasoning in Social Science research. Particularly, we focus on foundational elements to fit models under the Bayesian paradigm. We aim to offer a frame of reference for a broad audience, not necessarily with specialized knowledge in Bayesian…
Erling W. Rognli, Rune Zahl‐Olsen, Sondre Sverd Rekdal, Asle Hoffart + 1 more
'Thomas Bjerregaard Bertelsen'] Bayesian statistical approaches offer nuanced, detailed, and intuitive analyses, even with small sample sizes. Although these qualities are highly relevant for researchers in child and adolescent mental health, Bayesian methods are still quite rarely employed. This editorial perspective…
Natalia Levshina
In recent years, Bayesian statistics has gained traction across a wide range of scientific disciplines. This paper explores the growing application of Bayesian methods within the field of linguistics and considers their future potential. A survey of articles from different linguistics journals indicates that Bayesian…
Sanjay Chaudhuri, Yin Teng
In recent times empirical likelihood has been widely applied under Bayesian framework. Markov chain Monte Carlo (MCMC) methods are frequently employed to sample from the posterior distribution of the parameters of interest. However, complex, especially non-convex nature of the likelihood support erects enormous…
Tom Charnock, Laurence Perreault-Levasseur, François Lanusse
In recent times, neural networks have become a powerful tool for the analysis of complex and abstract data models. However, their introduction intrinsically increases our uncertainty about which features of the analysis are model-related and which are due to the neural network. This means that predictions by neural…
Xin Yan, Goshi Ogita, Shuji Ishihara, Kaoru Sugimura
Cell-based mechanical models, such as the Cell Vertex Model (CVM), have proven useful for studying the mechanical control of epithelial tissue dynamics. We recently developed a statistical method called image-based parameter inference for formulating CVM model functions and estimating their parameters from image data…
Authors not listed
The political, social and economic consequences of climate change drastically influence the requirements of modern energy systems and its components. This includes not only energy production but also concepts and innovations for its storage, especially in magnitudes of gigawatt hours. Carnot batteries, which convert…
Minas Karamanis
Over the past few decades, the volume of astronomical and cosmological data has increased substantially. In response to that, a variety of astrophysical models have been proposed to explain the plethora of observations. As the information provided by the data is always incomplete and uncertain, inferring the properties…
Chenxi Sui, Ziyang Jiang, Genesis Higueros, David Carlson + 1 more
High-performance batteries are poised for electrification of vehicles and therefore mitigate greenhouse gas emissions, which, in turn, promote a sustainable future. However, the design of optimized batteries is challenging due to the nonlinear governing physics and electrochemistry. Recent advancements have…
Jacques Balayla
We define the information threshold as the point of maximum curvature in the prior vs. posterior Bayesian curve, both of which are described as a function of the true positive and negative rates of the classification system in question. The nature of the threshold is such that for sufficiently adequate binary…
Russell J. Bowater
An overview is presented of a general theory of statistical inference that is referred to as the fiducial-Bayes fusion. This theory combines organic fiducial inference and Bayesian inference. The aim is that the reader is given a clear summary of the conceptual framework of the fiducial-Bayes fusion as well as pointers…
Prem Jagadeesan, Karthik Raman, Arun K Tangirala
Computational modelling of dynamical systems often involves many free parameters estimated from experimental data. The information gained from an experiment plays a crucial role in the goodness of predictions and parameter estimates. Optimal Experiment Design (OED) is being used to choose an experiment containing…
Samidha Shetty, Gordon Brittan Jr., Prasanta S. Bandyopadhyay, Dawn E. Holmes
'Dawn E. Holmes'] Empirical Bayes-based Methods (EBM) is an increasingly popular form of Objective Bayesianism (OB). It is identified in particular with the statistician Bradley Efron. The main aims of this paper are, first, to describe and illustrate its main features and, second, to locate its role by comparing it…
Ya’acov Ritov
We argue that the Bayesian paradigm, of a prior which represents the beliefs of the statistician before observing the data, is not feasible in ultra-high dimensional models. We claim that natural priors that represent the a priori beliefs fail in unpredictable ways under values of the parameters that cannot be honestly…
Sophie W. Berkhout, Julia M. Haaf, Quentin F. Gronau, Daniel W. Heck + 1 more
'Eric-Jan Wagenmakers'] Researchers conduct meta-analyses in order to synthesize information across different studies. Compared to standard meta-analytic methods, Bayesian model-averaged meta-analysis offers several practical advantages including the ability to quantify evidence in favor of the absence of an effect…
Nickolas Gantzler, Aryan Deshwal, Janardhan Rao Doppa, Cory Simon
Our objective is to search a large candidate set of covalent organic frameworks (COFs) for the one with the largest equilibrium adsorptive selectivity for xenon (Xe) over krypton (Kr) at room temperature. To predict the Xe/Kr selectivity of a COF structure, we have access to two molecular simulation techniques: (1) a…
Nikola Sekulovski, Maarten Marsman, Eric-Jan Wagenmakers
Bayes factor hypothesis testing provides a powerful framework for assessing the evidence in favor of competing hypotheses. To obtain Bayes factors, statisticians often require advanced, non-standard tools, making it important to confirm that the methodology is computationally sound. This paper seeks to validate Bayes…
Yui Hayashi, Shun Katakami, Shigeo Kuwamoto, Kenji Nagata + 3 more
'Masaichiro Mizumaki' 'Masato Okada' 'J. Ilavsky'] A Bayesian method is proposed for quantitatively selecting a mathematical model of a sample for small-angle scattering. The performance of this method is evaluated through numerical experiments on artificial data for a sample containing a mixture of multiple spherical…
Yong Li, Hefei Liu, Rubing Li, Lei Shi
Variable selection has always been an important issue in statistics. When a linear regression model is used to fit data, selecting appropriate explanatory variables that strongly impact the response variables has a significant effect on the model prediction accuracy and interpretation effect. redThis study introduces…
David Meijer, Roberto Barumerli, Robert Baumgartner
Interpreting sensory prediction errors can be challenging in volatile environments because they can be caused by stochastic noise or by outdated predictions. Noisy signals should be integrated with prior beliefs to improve precision, but the two should be segregated when environmental changes render prior beliefs…
Shaowei Lin, Chanchan Hu, Zhifeng Lin, Zhijian Hu + 1 more
Background Interaction identification is important in epidemiological studies and can be detected by including a product term in the model. However, as Rothman noted, a product term in exponential models may be regarded as multiplicative rather than additive to better reflect biological interactions. Currently, the…
Jérôme Eberhardt, Markus Lill, Torsten Schwede
This study introduces a novel Bayesian Optimization (BO) method to support the design and optimization of bioactive peptide sequences in the context of a fully automated closed-loop Design-Make-Test (DMT) pipeline. Using the major histocompatibility complex class I receptor system as test case, we showed that BO is…
Jonas Verhellen
In recent years, there have been considerable academic and industrial research efforts to develop novel generative models for high-performing, small molecules. Traditional, rules-based algorithms such as genetic algorithms [Jensen, Chem. Sci., 2019, 12, 3567-3572] have, however, been shown to rival deep learning…
Augustijn A.A. de Boer, Seyed Mostafa Kia, Saige Rutherford, Mariam Zabihi + 7 more
Normative modelling is an emerging technique for parsing heterogeneity in clinical cohorts. This can be implemented in practice using hierarchical Bayesian regression, which provides an elegant probabilistic solution to handle site variation in a federated learning framework. However, applications of this method to…
Authors not listed
Occupational chemical hazards pose profound risks to chemists in laboratory and industrial settings, encompassing acute and chronic exposures that imperil sensory organs (e.g., ocular, auditory, olfactory, dermal) and vital physiological systems. This manuscript delineates a multifaceted, innovative protocol suite…
Sterling Baird, Jason R. Hall, Taylor D. Sparks
Would you rather search for a line inside a cube or a point inside a square? This type of solution degeneracy often exists in physics-based simulations and wet-lab experiments, but constraining these degeneracies is often unsupported or difficult to implement in many optimization packages, requiring additional time and…
Sterling Baird, Jason R. Hall, Taylor D. Sparks
Would you rather search for a line inside a cube or a point inside a square? Physics-based simulations and wet-lab experiments often have symmetries (degeneracies) that allow reducing problem dimensionality or search space, but constraining these degeneracies is often unsupported or difficult to implement in many…