PPubMed8 Sep 2026
Genetic evidence and cross-species functional characterization implicate <i> CNN2 </i> in age-related macular degeneration susceptibility
Fei-Fei Cheng, Hao Mou, Zhenyu Liu, Chang-Jun Zhang + 7 more
Title: Significance Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss among older adults and is projected to affect approximately 288 million people worldwide by 2040. Identifying the genes and cellular mechanisms underlying established AMD risk loci is essential for…