12 papers · ranked by Valyu relevance
Hiroyuki Kusano, Takayuki Shiomi
Digital pathology has rapidly expanded over the past decade, driven by advances in whole-slide imaging and increasing demand for remote and data-integrated diagnostic workflows. However, many implementations remain limited to partial digitization, without fundamentally transforming laboratory and diagnostic processes.…
Mirna El Ghosh, Varvara Kalokyri, Maciej Bobowicz, Melanie Sambres + 11 more
Background Semantic interoperability in health care, essential for seamless integration of information systems, is partially achieved through the use of terminologies and common data standards that define the semantic structure of data. Various complexities arise when using real-world health care data, including…
Jos P Kanning, Habibollah Pirnejad, Awa A Gassama, Coralie R Arends + 6 more
Key Features1. The General Practice Database-Amsterdam, North Holland, Almere (GPD-ANHA) is hosted by the Department of General Practice of the Amsterdam University Medical Center (Amsterdam UMC) and was established in 2024 through the integration of the general-practice databases from the former Academic Medical…
Fubo Ma, Kang Li, Yangchao Yu, Lei Zhang + 3 more
Type I interferon (IFN-I) is an important class of cytokines that can inhibit tumuor progression through mechanisms such as immunomodulation of the tumuor microenvironment or targeting cellular components. Although various endogenous and exogenous IFN-I therapeutic strategies have been developed, reports of immune cell…
Panagiotis Douris, George Kodovazenitis
The integration of artificial intelligence (AI) into dentistry is reshaping clinical workflows, opening new possibilities for population-level public health monitoring. Machine learning approaches, such as convolutional neural networks and other deep learning architectures, are becoming more and more capable to exhibit…
Manuel Treutlein, Pascal Bothe, Marc Schmidt, Roman Hahn + 4 more
The last mile of the distribution grid is crucial for a successful energy transition, as more low-carbon technology like photovoltaic systems, heat pumps, and electric vehicle chargers connect to the low-voltage grid. Despite considerable challenges in operation and planning, researchers often lack access to suitable…
Marc-André Blanchette, Lilly Nguyen, Jean-Philip Hudon-Dionne, Geneviève Lavigne + 2 more
Background Physician referral rates to chiropractors remain low in Quebec, and few multidisciplinary clinics include both professions. Yet these settings represent a unique opportunity to study interprofessional collaboration in musculoskeletal care. This study aimed to identify facilitators and barriers to…
Andrea Ferrero, Giuseppe Anzillotti, Pietro Conte, Simonetta Resta + 6 more
This systematic review highlights that the regenerative capabilities of 3D-printed meniscal scaffolds are primarily driven by the complex interplay between biomaterials, architecture, degradation kinetics and biological activation rather than by polymer selection alone. Scaffold performance in preclinical models…
Akemi Morohashi, Satoshi Yamashita, Takahiro Imaizumi, Takuto Sano + 3 more
1## Introduction The use of real-world data (RWD) to generate real-world evidence (RWE) has expanded globally to support regulatory decision-making, postmarketing surveillance, and clinical research . Indeed, regulatory authorities worldwide have increasingly used RWE derived from routine electronic health records…
Ana Lúcia Leitão, Francisco J Enguita
The evolution of molecular visualization software represents a pivotal yet often underappreciated dimension of computational structural biology and bioinformatics. As the scale and complexity of structural datasets increase, spanning from cryo-electron microscopy reconstructions to proteome-wide AI-predicted models…
Jofen Kihlström, Martin Salzmann‐Erikson, Irene Hylander, Maria Lindberg
Adolescent substance use frequently co-occurs with mental-health difficulties and social adversity. Existing research highlights heterogeneous risk profiles and a paucity of integrated service models that bridge health- and social-care sectors. A qualitative case study was undertaken at the newly established MiniMaria…
Yasir Ahmed Mohammed Elhadi, Aminu S Abdullahi, Abdelrahman Mohamed Alblooshi, Abdulla Alhosani + 6 more
Background Robotic-assisted surgery (RAS) is increasingly being integrated into surgical services worldwide. Successful implementation of robotic surgical technologies depends not only on clinical effectiveness but also on public trust, perceptions of safety, and willingness to use technology-enabled care. In the…