8 papers · ranked by Valyu relevance
Mirna El Ghosh, Varvara Kalokyri, Maciej Bobowicz, Melanie Sambres + 11 more
Background Semantic interoperability in health care, essential for seamless integration of information systems, is partially achieved through the use of terminologies and common data standards that define the semantic structure of data. Various complexities arise when using real-world health care data, including…
Yuichi Kodama, Colman O’Cathail, Linda Yankie, {'email': '', 'name': '', 'type': 'author'}
Members of the International Nucleotide Sequence Database Collaboration (INSDC; [https://www.insdc.org/]()) collect, exchange, and preserve comprehensive open nucleotide sequence information and provide tools for its access. The INSDC has stated its commitment to welcoming new members into the collaboration to be more…
Julius F. Witte, Artur Lissin, Isabel Schober, Christian Ebeling + 16 more
The vast amount of existing data on microbial strains holds immense potential to revolutionize bioindustry through the application of Artificial Intelligence (AI). However, the training of robust predictive AI models requires large-scale, unified, and non-redundant microbial datasets, which is currently severely…
Manuel Treutlein, Pascal Bothe, Marc Schmidt, Roman Hahn + 4 more
The last mile of the distribution grid is crucial for a successful energy transition, as more low-carbon technology like photovoltaic systems, heat pumps, and electric vehicle chargers connect to the low-voltage grid. Despite considerable challenges in operation and planning, researchers often lack access to suitable…
Maria Juliana Rodriguez-Cubillos, Tomasz Zieliński, Jason R. Swedlow, T. Ian Simpson + 1 more
Ensuring the availability and accessibility of research data is fundamental to advancing knowledge, as codified in the FAIR principles (Findable, Accessible, Interoperable, and Reusable). Accurate metadata documentation is indispensable for meeting these principles; however, entries in deposition databases often…
Huihai Wu, Ashleigh Lister, Iain Macaulay, Katie Long + 10 more
Single-cell and spatial transcriptomics are transforming our understanding of cellular heterogeneity and tissue organization, yet their analytical complexity remains a major bottleneck. Here, we present EISCA and EISTA, two standardized, end-to-end pipelines for single-cell RNA- seq and imaging-based spatial…
Akemi Morohashi, Satoshi Yamashita, Takahiro Imaizumi, Takuto Sano + 3 more
1## Introduction The use of real-world data (RWD) to generate real-world evidence (RWE) has expanded globally to support regulatory decision-making, postmarketing surveillance, and clinical research . Indeed, regulatory authorities worldwide have increasingly used RWE derived from routine electronic health records…
Noémie Aubert Bonn, Andrew J. Stewart, Lukas Hughes-Noehrer
Open research practices are increasingly promoted to improve research transparency, reproducibility, accessibility, and societal impact. Despite growing support from research funders, institutions, and policy initiatives, adoption remains uneven across disciplines and research communities. This study examined perceived…