6 papers · ranked by Valyu relevance
Emily Cordeiro, Daniela Herrera Chaves, Nima Talei, Iván Castro + 6 more
Statistical learning (SL) has been proposed to depend on the hippocampus, but traditional neuropsychological theories of long-term memory posit that the hippocampus is only necessary for explicit memory processes, not implicit memory processes. To reconcile these two accounts, we exposed 27 temporal lobe epilepsy (TLE)…
Jörn A. Quent, Kaixiang Zhuang, Xinyu Liang, Debin Zeng + 5 more
Detecting novelty is fundamental to adaptive memory, yet the neural comparisons that allow new events to be distinguished from prior experience are not fully understood. Hippocampal novelty signals are often framed as associative comparator responses that register violations of learned relationships. However…
Justin D Shin, Michael Satchell, Paul Miller, Shantanu P Jadhav + 2 more
REM (rapid eye movement) and non-REM (NREM) sleep stages contribute to systems memory consolidation in hippocampal-cortical circuits. However, the physiological mechanisms underlying REM memory processes remain relatively unclear compared to NREM memory reactivation. Here we report, in rodents, the existence of…
Prince Okyere, Junheng Li, Tobias Raufeisen, Ketevan Alania + 10 more
Memory consolidation during sleep depends on the precisely timed coordination of hippocampal reactivation with cortical slow oscillations and spindles. In humans this coupling has been characterised correlationally, while causal investigations have required intracranial stimulation in restricted patient cohorts or used…
Hong-Di Huang, Yun-Chao Ji, Long Zhang, Min Xu + 20 more
The ANK2 gene mutations are marked risk factors for autism spectrum disorder, one of the neurodevelopmental disorders (NDDs) that often extends into adulthood and has a complex etiology involving genetic and environmental factors. ANK2 encodes 2 major isoforms, AnkB-220 (220-kDa isoform of ankyrin-B) and giant…
John Tower
Biological information is generally thought to be subject to selection for faithful maintenance. However, accurate preservation is often combined with regulated mechanisms that generate state change. Selectively advantageous instability (SAI) is modeled here as instability that is favored because useful alternatives…