5 papers · ranked by Valyu relevance
Federico Vannuccini, Yari Ciani, Vera Mugoni, Orsetta Quaini + 20 more
Circulating analytes in cancer patients capture tumor-related signals. We profiled matched extracellular vesicle (EV) total RNA and cell-free DNA (cfDNA) from the same plasma aliquots of chemo-naive metastatic castration-resistant prostate cancer (mCRPC) patients treated with Enzalutamide (n=54 patients, n=119…
Yajing Chen, Xiaohuan Du, Fang Li, Shuwei Yuan + 4 more
1## Introduction Neurological disorders are a leading cause of disability worldwide, yet disease-modifying therapies remain scarce. A central challenge in their treatment lies in the etiological heterogeneity of these conditions . ad, PD, TBI, and ischemic stroke arise from distinct primary insults but converge upon…
Yao Shen, Ziyang Yu, Qinfeng Zhu, Zhiyong Zhao + 7 more
Bridging the gap between macroscopic neuroimaging and microscopic histology remains a challenge in neuroscience. Here, we present a technical feasibility study of diffusion MR microscopy (dMRM) in the ex vivo human hippocampus using a 14.1 T ultrahigh-field MRI system. Mid-hippocampal blocks from control and…
Yi Peng, Suobing Qin, Xiwen Li, Lijun Wan + 1 more
1## Introduction Clear cell renal cell carcinoma (ccRCC) is the most common and invasive subtype of kidney cancer, accounting for approximately 75% of cases, with a low 5-year survival rate for metastatic disease . In recent years, advances in diagnostic technology have improved the early detection rate of RCC.…
Wei-shan Li, Gregory P. Way
Pairing label-free microscopy with virtual staining could reduce the cost and experimental burden of fluorescence microscopy, but its impact is conditional on generalizable inference. Most virtual staining studies assess performance using image quality assessment (IQA) metrics developed for natural images, yet how well…