BbioRxiv9 Sep 2026
An atlas of the *C. elegans* starvation response reveals that transcription is necessary to initiate transcriptional silencing in quiescent primordial germ cells
Jingxian Chen, Sharan Surya, Rojin Chitrakar, Jenna R. Valley + 2 more
Starvation profoundly impacts development, but how different tissues respond to starvation is unclear. We generated a cellular atlas of gene expression in fed and starved C. elegans L1 larvae. We identified 79 cell types in both conditions, and we detected ∼98% of protein-coding genes, 44% of which were differentially…