11 papers · ranked by Valyu relevance
Quancai Li, Jing Liang, Jiayu Wang, Qian Wang + 4 more
Eutectic electrolytes are attractive for zinc-based energy storage owing to their green chemistry attributes and intrinsic stability; however, their practical deployment is limited by severe polarization stemming from sluggish ion transport and strong solvation. Here, we propose a ternary water-deficient eutectic…
Peter F. Pelz, Tobias Meck
For nearly a century, the physical origin of metabolic scaling has remained unresolved: metabolism is proportional to body mass in small organisms but follows Kleiber’s three-quarter-power law in larger animals. We derive both regimes from the Metabolic Holon (MH), a locally optimized capillary–tissue oxygen-supply…
Andreas Carlsson, Ulf Olsson, Sara Linse
In Alzheimer’s disease (AD), the aggregation of amyloid β (Aβ) peptides has been linked to disease pathology. Once aggregates have formed, existing fibrils catalyze the formation of new fibrils in a runaway process associated with neuro degeneration. One component of the cellular defense system against amyloid…
Yao Shen, Ziyang Yu, Qinfeng Zhu, Zhiyong Zhao + 7 more
Bridging the gap between macroscopic neuroimaging and microscopic histology remains a challenge in neuroscience. Here, we present a technical feasibility study of diffusion MR microscopy (dMRM) in the ex vivo human hippocampus using a 14.1 T ultrahigh-field MRI system. Mid-hippocampal blocks from control and…
Lou Thomas, Gaia Scerif, Hodo Yusuf, Mackenzie Laird + 3 more
Diffusion decision models (DDMs) offer the potential to go beyond standard accuracy and response-time indices to better understand perceptual decision-making in autism. One unanswered question is whether autistic participants can flexibly adjust the speed and accuracy of their decision-making according to task demands.…
Minha Park, Shinwoo Kim, Seokhyun Moon, Hyeongwoo Kim + 2 more
Co-folding models accurately predict biomolecular complexes, but how their internal representations support joint structure prediction remains unclear. We analyze the Boltz-1 trunk by decomposing its pair representation into intra-chain and inter-chain blocks and applying ablation, layer-wise representation geometry…
Jeffrey D. Walker, Paul Aparicio, Shreya Saxena, Nicholas G. Hatsopoulos + 1 more
The ability to record neural populations during natural behavior now allows us to ask whether canonical motor-cortical dynamics, defined largely in constrained reaches to static targets, also organize self-paced, feedback-rich actions that require continuous correction. We recorded sensorimotor cortex in marmosets…
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki + 15 more
Many nanoscale materials, ranging from environmental particulates to carrier-free nanomedicine platforms, enter the human body, yet their metabolic fates remain poorly understood. This process involves complex physical changes and molecular transformations within lysosomes; however, the particle-to-molecule…
Vladimir Urban, Zorica Milosevic, Zoran Bukumiric, Katarina Obradovic + 6 more
Background The aim of this study was to identify imaging predictors of upgrade to invasive carcinoma (IC) in patients with biopsy-proven ductal carcinoma in situ (DCIS) based on morphological features and semi-quantitative parameters derived from dynamic contrast-enhanced breast magnetic resonance imaging (DCE-MRI).…
Alba Cortés‐Martínez, Francisco Sánchez‐Férez, José A. Suárez del Pino, Sergio Royuela + 3 more
The development of porous materials that combine low-temperature meltability with high gas uptake remains a major challenge. Herein, we report Cu-BCN-5, a polymer-grafted Cu(II) metal-organic polyhedron (MOP), as a scalable melt-processable material with intrinsic porosity. This material melts at 44°C while preserving…
Suyi Zhou, Zhiming Zhen, Cheng Lai, Peiyu Huang + 6 more
1## Introduction Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease (AD), characterized by progressive loss of dopaminergic neurons and the abnormal accumulation of α-synuclein . In addition to classical neurodegenerative features, growing evidence suggests that…