9 papers · ranked by Valyu relevance
Daniel S. Malawsky, Laura Hegemann, Olivia Wootton, Alexandra Karoline Havdahl + 2 more
Parental genotypes may influence offspring outcomes through the environments parents provide, a process known as genetic nurture, but estimating such effects from polygenic scores is complicated jointly by measurement error, unobserved genetic variation, and assortative mating. Here, we introduce RAVEL, a structural…
Ivan Specht, Soyoon Park, Seyone Chithrananda, Claudia L. Driscoll + 3 more
Viral mutation forecasting plays a key role in pandemic preparedness by enabling researchers to anticipate novel variants and design proactive interventions. Evolutionary histories, represented as phylogenetic trees, offer key insights into the emergence of past and present strains, yet their role in predicting future…
Lianne Gahan, Adélaïde Raguin, Partho Sakha De
Lignin’s complex and highly branched architecture plays a critical role in biomass utilisation. Yet, unravelling the intricate relation between lignin’s measurable structural features and the underlying biosynthesis dynamics remains a major challenge. This difficulty stems from the variability in monolignol and bond…
Eliezer Masliah
How transient neural representations become integrated and stable enough to function as internal neural models remains incompletely understood. Grounded in efficient coding, Bayesian and predictive frameworks, recurrent and attractor dynamics, neural state-space models, and systems neuroscience, the Principle of…
Fabio Barteri, Arcadi Navarro, Omar E. Cornejo
Continuous traits evolve unevenly across phylogenies, producing patterns of phenotypic differentiation shaped by both shared ancestry and lineage-specific change. Identifying exceptionally differentiated species pairs may therefore improve genome–phenome comparisons, but existing approaches rarely rank such contrasts…
John Tower
Biological information is generally thought to be subject to selection for faithful maintenance. However, accurate preservation is often combined with regulated mechanisms that generate state change. Selectively advantageous instability (SAI) is modeled here as instability that is favored because useful alternatives…
Yawako W. Kawaguchi, Masaru Kono, Minako Isoda, Kensuke Kawade + 7 more
Molecular evolutionary rates vary widely among organisms, yet the biological mechanisms underlying this variation and its evolutionary consequences remain poorly understood. In plants, the absence of an early-segregated germline raises the possibility that growth- and environment-dependent physiological processes could…
Rui Zhang, Huamin Liu, Shan Jiang, Zhichao Xu + 4 more
The Mongolian Plateau, a typical arid and semi-arid zone in Eurasia, is characterized by highly heterogeneous and fragmented wetland habitats. Phragmites australis, a common wetland species in this region, exhibits remarkable adaptability. Unraveling the coordination between phylogenetic history and local environmental…
Hayato Idei, Keisuke Suzuki, Yuichi Yamashita
Mindfulness has established psychological benefits, such as stress reduction and emotional regulation; however, the underlying computational mechanisms, particularly in relation to mind-wandering, remain unclear. This study aimed to present a hierarchical recurrent neural network-based agent model grounded in the free…