24 papers · ranked by Valyu relevance
Dominic K. Devlin, Austen R. D. Ganley, Nobuto Takeuchi, Lin Wan
Morphogenesis of complex body shapes is reproducible despite the noise inherent in the underlying morphogenetic processes. However, how these morphogenetic processes work together to achieve this reproducibility remains unclear. Here, we ask how this reproducibility is achieved by evolving complex morphologies in a…
Hui Lu, Yueyue Zhang, Boying Xu, Di Tian + 3 more
Cell shape plays a fundamental role in bacterial physiology, yet the evolutionary stability of morphological adaptations remains poorly understood. Our previous work suggested that Escherichia coli can evolve a spherical form under primordial-like conditions. Here, we extended experimental evolution for approximately…
Oded Agam, Erez Braun
Developmental robustness is framed as progress through a fixed Waddington-type landscape. We argue that in morphogenesis this landscape evolves through coupled bio-signaling, mechanical, and physiological processes, while fluctuations aid exploration. In Hydra regeneration, stochastic Ca activity plays a major role in…
Hyunwoo Jung, Campbell Rolian, David S. Strait, Karen L. Baab
2.3.2#### Duration and Outcome of Simulations Viability selection simulations were conducted 1000 times per scenario to generate a distribution of simulation outcomes. We recorded the mean number of generations required for the source population to “reach” the target population in these 1000 simulations. Additionally…
W. Bryan Jennings
A graphical scaling model, named the “geometric-similarity-first model,” is developed to explain allometric trait divergence over recent evolutionary time. According to the model, traits first undergo geometric scaling with body size changes. In step two, traits go through evolutionary allometric scaling owing to a…
Yoshiyuki T. Nakamura, Chikara Furusawa, Kunihiko Kaneko
Embryonic development in multicellular organisms exhibits diverse morphogenetic patterns, which can generally be categorized into fundamental types such as monolayer and multilayer spheres, as well as cell masses. Furthermore, we identify two distinct processes for the formation of spherical structures. These basic…
K. Ege de Bruin, Kyrre Glette, Kai Olav Ellefsen
—Evolutionary Robotics offers the possibility to design robots to solve a specific task automatically by optimizing their morphology and control together. However, this co-optimization of body and control is challenging, because controllers need some time to adapt to the evolving morphology - which may make it…
Elliot M. Butterworth, Tim Rogers, Matthew A. Wills
Attempts to quantify biological complexity often consider intrinsic structural properties at a chosen hierarchical level and resolution, such as counts of body parts and their degree of differentiation. These measures are inherently \emph{syntactic}, being concerned with the information needed to specify an arrangement…
Charlie Longtine, Hannah A. Grunwald, Stephen Treaster, Matthew P. Harris + 1 more
The evolution of flippers for wing-powered diving in penguins is a striking example of tetrapod limb specialization. The modern penguin flipper is structurally reinforced by a characteristic dorsoventral ‘flattening’ of the long bones accompanied by a reduction in distal forelimb musculature, features which emerged…
Fabio A. Machado, Anna Penna, Diogo Melo, Barbara A. Costa + 7 more
Directional selection is often viewed as a transient force in macroevolution, with its signal eroded over time by stabilizing and fluctuating selection. Yet, transitions into new adaptive zones are predicted to impose strong and sustained selective pressures that may leave a detectable signature even across deep…
Authors not listed
Polyacrylonitrile flower-like particles (PANFs), as hierarchical superstructures, have recently found applications in catalysis, batteries, sensing, and gas absorption. Yet, precise control over their size and morphology which dictate their properties remains challenging, as the role of reaction parameters in their…
Elías Adán Warshaw, Suresh Anmol Singh, Michael James Benton
The first truly terrestrial apex predators were carnivorous synapsids, which emerged in the Permian over 260 million years ago and evolved against a backdrop of harsh ecological change. In many ways, these predators mirrored feeding modes and evolutionary trends seen in their much later descendants, the flesh-eating…
Mihajlo Milić, Michael Matschiner, Naomi De Leo, Gertrud E. Rössner + 1 more
Despite their currently scarce taxonomic diversity, rhinocerotoids were among the most evolutionarily successful clades of large herbivorous mammals throughout the Caenozoic. Within an array of morphological adaptations, the cranial horn represents the clade’s most remarkable and name-giving feature, imposing…
Hadrien Oliveri, Christophe Godin, Ibrahim Cheddadi
Plant morphogenesis relies on dynamic growth deformations at the cell and tissue scales driven by osmotic fluxes. A mechanistic understanding of this phenomenon demands a physical framework that integrates cell imbibition, tissue mechanics, and water fluxes, as well as their biophysical and molecular regulations…
Authors not listed
Assembly of block copolymers (BCPs) with epoxy is useful to enhance the mechanical toughness of 3D-printable epoxy inks. Recently, ionic liquids (ILs) like 1-Ethyl-3-Methylimidazolium dicyanamide ([EMIM][DCA]) have enhanced the self-assembly of pure BCP, enabling the formation of a controlled nanostructure. However…
Authors not listed
RNA droplets assembled from co-transcriptionally folded nanostructures have recently emerged as a promising platform for constructing protocells and minimal synthetic cell models. In these systems, a custom-designed DNA template encodes an RNA nanostar, which is produced by transcription and self-assembles into…
Stephanie Y. Chia, Anshuman Swain, Nathaniel Josephs, Lizhen Lin + 1 more
Understanding why some viable body forms never evolve can reveal how ecological and evolutionary forces shape biodiversity. We investigate this question in the Passeroidea, a large group of songbirds, by analysing their morphological trait space using topological data analysis and ancestral state reconstruction. We…
Meraj Ahmed, Lahcen Akerkouch, Aaron Vanyo, Amanda Haage + 1 more
This work investigates the role of the cancer cell morphology and elasticity on the deformation patterns under shear-flow in a micro-channel. A novel hybrid continuum-particle framework is developed to simulate cancer-cell dynamics. Cell membrane and nucleus geometries are reconstructed from microscopic images and…
Authors not listed
Self-assembly, the spontaneous organization of molecular components into ordered structures without external intervention, offers a powerful route to complex nanomaterials, yet the molecular-level pathways, particularly under non-equilibrium conditions, remain poorly understood. We track in real time the formation of…
Authors not listed
Chirality at the nanoscale has emerged as a powerful design parameter for engineering light-matter interactions, catalytic activity, and biological recognition. Among inorganic nanomaterials, plasmonic gold nanostructures are particularly attractive owing to their tunable optical resonances and compatibility with…
Authors not listed
Vertex models have been established as powerful tools for the cell-based simulation of epithelial tissues as they allow a detailed description of their mechanical development with respect to the properties of individual cells. Thus, they suit the challenges of simulating intestinal organoids which arise from the…
Charles C. Roseman, Benjamin M. Auerbach
The extended evolutionary synthesis (EES) is a school of thought that maintains that genetic determination and natural selection are over-emphasized in the study of evolution at the expense of non-genetic inheritance and processes of evolution beyond selection. Its proponents call for the de-emphasis of genetics and…
Liudmyla Vasylenko, Adi Livnat
At the fundamental conceptual level, two alternatives have traditionally been considered for how mutations arise and how evolution happens: 1) random mutation and natural selection, and 2) Lamarckism. Recently, the theory of Interaction-based Evolution (IBE) has been proposed, according to which mutations are neither…
Hiroyuki Iizuka
This study introduces a novel theoretical framework, the Stacked Autoencoder Evolution Hypothesis, which proposes that biological evolutionary systems operate through multi-layered self-encoding and decoding processes, analogous to stacked autoencoders in deep learning. Rather than viewing evolution solely as gradual…