12 papers · ranked by Valyu relevance
Song Deng, Dong Yue, Le-chan Yang, Xiong Fu + 2 more
'Jayoung Kim'] For high-dimensional and massive data sets, traditional centralized gene expression programming (GEP) or improved algorithms lead to increased run-time and decreased prediction accuracy. To solve this problem, this paper proposes a new improved algorithm called distributed function mining for gene…
Aditi T. Merchant, Samuel H. King, Eric Nguyen, Brian L. Hie
Generative genomics models can design increasingly complex biological systems. However, effectively controlling these models to generate novel sequences with desired functions remains a major challenge. Here, we show that Evo, a 7-billion parameter genomic language model, can perform function-guided design that…
Bing Zhang, Guoyan Huang, Yuqian Wang, Haitao He + 2 more
'Zhong-Ke Gao'] As the quality of crucial entities can directly affect that of software, their identification and protection become an important premise for effective software development, management, maintenance and testing, which thus contribute to improving the software quality and its attack-defending ability. Most…
Zhuang Xiong, Yunfeng Zhang, Xiaodie Chen, Ajia Sha + 6 more
This study utilized 16S rRNA high-throughput sequencing technology to analyze the community structure and function of endophytic bacteria within the roots of three plant species in the vanadium-titanium-magnetite (VTM) mining area. The findings indicated that mining activities of VTM led to a notable decrease in both…
Jing Chen, Aijun Liu, Hongjun Zhang, Shengyi Yang + 3 more
'Ning Zhou' 'Peng Li'] With the rapid development of AI and big data mining technologies, computerized medical decision-making has become increasingly prominent. The aim of high-utility pattern mining (HUPM) is to discover meaningful patterns in medical databases that contribute to maximizing the utility from the…
Patryk Burek, Frank Loebe, Heinrich Herre
Background Gene Ontology (GO) is the largest resource for cataloging gene products. This resource grows steadily and, naturally, this growth raises issues regarding the structure of the ontology. Moreover, modeling and refactoring large ontologies such as GO is generally far from being simple, as a whole as well as…
Jiao Yue, Dongpeng Zhang, Miaomiao Cao, Yukui Li + 4 more
Nine land types in the northern mining area (BKQ) (mining land, smelting land, living area), the old mining area (LKQ) (whole-ore heap, wasteland, grassland), and southern mining area (NKQ) (grassland, shrubs, farmland) of Xikuang Mountain were chosen to explore the composition and functions of soil bacterial…
Robert Starke, Petr Capek, Daniel Morais, Nico Jehmlich + 1 more
Unveiling the relationship between taxonomy and function of the microbiome is crucial to determine its contribution to ecosystem functioning. However, while there is a considerable amount of information on microbial taxonomic diversity, our understanding of its relationship to functional diversity is still scarce. Here…
Moises A. Rojas, Gladis Serrano, Jorge Torres, Jaime Ortega + 8 more
Microbial communities inhabiting mining environments harbor a diverse array of bacteria with specialized metabolic capacities adapted to extreme conditions. Here, we utilized comparative genome-resolved metagenomics of a high-quality Illumina-sequenced sample from the Cauquenes copper tailing in central Chile. We…
Laura Kaikkonen, Malcolm R. Clark, Daniel Leduc, Scott D. Nodder + 4 more
Increasing interest in seabed resource use in the ocean is introducing new pressures on deep-sea environments, the ecological impacts of which need to be evaluated carefully. The complexity of these ecosystems and the dearth of comprehensive data pose significant challenges to predicting potential impacts. In this…
Beth N. Orcutt, James Bradley, William J. Brazelton, Emily R. Estes + 7 more
Interest in extracting mineral resources from the seafloor through deep-sea mining has accelerated substantially in the past decade, driven by increasing consumer demand for various metals like copper, zinc, manganese, cobalt and rare earth elements. While there are many on-going discussions and studies evaluating…
Laura Kaikkonen, Inari Helle, Kirsi Kostamo, Sakari Kuikka + 4 more
Seabed mining is approaching the commercial mining phase across the world’s oceans. This rapid industrialization of seabed resource use is introducing new pressures to marine environments. The environmental impacts of such pressures should be carefully evaluated prior to permitting new activities, yet observational…