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Search · four archives
11 papers · ranked by Valyu relevance
Meng Jiao, Feng Liu
Electroencephalography (EEG)/Magnetoencephalography (MEG) source imaging aims to seek an estimation of underlying activated brain sources to explain the observed EEG/MEG recording. Due to the ill-posed nature of inverse problem, solving EEG/MEG Source Imaging (ESI) requires design of regularization or prior terms to…
Elisabetta Vallarino, Ana Sofia Hincapié, Karim Jerbi, Richard Leahy + 3 more
The accurate characterization of cortical functional connectivity from Magnetoencephalography (MEG) data remains a challenging problem due to the subjective nature of the analysis, which requires several decisions at each step of the analysis pipeline, such as the choice of a source estimation algorithm, a connectivity…
Eneko Uruñuela, Javier Gonzalez-Castillo, Charles Zheng, Peter Bandettini + 1 more
Blind estimation of neuronal-related activity from functional magnetic resonance imaging (fMRI) data of resting-state, naturalistic paradigms or clinical conditions can be performed with paradigm free analysis methods such as hemodynamic deconvolution. These methods usually employ a linear hemodynamic convolution model…
Anni S. Halkola, Kaisa Joki, Tuomas Mirtti, Marko M. Mäkelä + 2 more
In many real-world applications, such as those based on patient electronic health records, prognostic prediction of patient survival is based on heterogeneous sets of clinical laboratory measurements. To address the trade-off between the predictive accuracy of a prognostic model and the costs related to its clinical…
Alain J. Mbebi, Zoran Nikoloski
Despite extensive research efforts, reconstruction of gene regulatory networks (GRNs) from transcriptomics data remains a pressing challenge in systems biology. While non-linear approaches for reconstruction of GRNs show improved performance over simpler alternatives, we do not yet have understanding if joint modelling…
Lea Duncker, Kiersten M. Ruda, Greg D. Field, Jonathan W. Pillow
An important problem in systems neuroscience is to characterize how a neuron integrates sensory inputs across space and time. The linear receptive field provides a mathematical characterization of this weighting function, and is commonly used to quantify neural response properties and classify cell types. However…
Maliheh Miri, Vahid Abootalebi, Enrico Amico, Hamid Saeedi-Sourck + 2 more
Taking advantage of the human brain functional connectome as an individual’s fingerprint has attracted great research in recent years. Conventionally, Pearson correlation between regional time-courses is used as a pairwise measure for each edge weight of the connectome. Building upon recent advances in graph signal…
Griffin S. Hampton, Ryan Neff, Zezheng Song, Mustapha Bouhrara + 2 more
Myelin water fraction (MWF) mapping in the central nervous system is a topic of intense research activity. One framework for this requires parameter estimation from a decaying biexponential signal. However, this is often an ill-posed nonlinear problem resulting in unreliable parameter estimates. For linear…
Riccardo De Feo, Ekaterina Antipushina, Ivan Tyukin, Yury Koush
While functional Magnetic Resonance Imaging (fMRI) can provide detailed information regarding the functional activity of the whole brain, its cumbersome experimental setting and high cost prevent its application in ecological conditions. This represents a challenge in the context of neurofeedback therapy. To address…
Guanghui Zhang, Xinran Wang, Steven J. Luck
Regularization has been extensively used in multivariate pattern classification (MVPA; decoding) of EEG data to mitigate the risk of overfitting. N-fold cross-validation is also used to mitigate this risk, and it is often combined with averaging across trials to improve the signal-to-noise ratio. However, the impact of…
Søren A. Fuglsang, Kristoffer H. Madsen, Oula Puonti, Hartwig R. Siebner + 1 more
Regression is a principal tool for relating brain responses to stimuli or tasks in computational neuroscience. This often involves fitting linear models with predictors that can be divided into groups, such as distinct stimulus feature subsets in encoding models or features of different neural response channels in…