20 papers · ranked by Valyu relevance
Werner Greve
This paper argues that the project of a lifespan perspective in developmental psychology has not yet been systematically pursued. Overall, the number of age-specific papers far outweighs the number of lifespan approaches, and even approaches that focus on the lifespan as a whole are often restricted to adulthood.…
David Cohen, Axel Baptista
From the above, we understand that the child develops in an environment of extreme variety. From a systemic perspective, environmental factors are considered in a gradient of distance from the child . At the most proximal, we isolate the contribution of toxic environmental factors that will have a direct effect on…
Livio Provenzi, Giorgia Bussu, Valentina Riva
Child development is a non-linear, chaotic process that can be observed across different levels of analysis, each one being only partially predictable and as a whole concerning an open, interacting system that cannot be reduced to simplistic observations of isolated processes concerning the individual child alone…
Jolinde M.R. Vlaeyen, Bas van Boekholt, Franziska Wegdell, Raymond Katumba + 3 more
Human development is marked by extended immaturity, necessitating extended care throughout infancy and childhood, facilitating advanced cognitive, social, and cultural skill acquisition. Parallels of extended development are also present in our closest living relatives, bonobos (Pan paniscus) and chimpanzees (Pan…
Rolando Gonzales Martínez, Hinke Haisma
Children's growth is more than height and weight. In this document we introduce and explain the Multidimensional Index of Child Growth (MICG), developed by the International Union for Nutrition Sciences (IUNS) Task Force "Towards a Multidimensional Approach for Child Growth," to operationalize a capability- and…
Alexander Muacevic, John R Adler, Akanksha Likhar, Prerna Baghel + 1 more
'Manoj Patil'] In human beings, the development of a child involves biological, emotional, and psychological changes that happen between birth and the conclusion of adolescence. Childhood is divided into three stages: early childhood, middle childhood, and late childhood (preadolescence). Early childhood is typically…
Aline Pereira da Silva, George Oliveira Silva, Marta Rovery de Souza
Child development consists of a process that involves multiple factors interrelated to the acquisition of children's skills in different areas, such as language, motor, cognitive, emotional, and social. Although extensively explored in literature, there is a gap in how vulnerabilities faced by families can influence…
Mark Stefik, Robert L. Price
In contrast, mainstream approaches have led to impressive feats and commercially valuable AI systems. The approaches include deep learning and generative AI (e.g., large language models) and manually constructed symbolic modeling. However, manually constructed AIs tend to be brittle even in circumscribed domains.…
Kefale Mitiku, Tilaye Nega, Mastewal Arefaynie, Degalem Tilahun + 4 more
'Bereket Kefale' 'Yitayish Damtie' 'Bezawit Adane' 'Melaku Yalew'] Background Child psychomotor development and factors affecting it today is the subject of interest of many studies, in particular by the experts involved in the protection and improvement of children’s health. There is limited evidence on developmental…
Alexander Kriebitz, Caitlin Corrigan, Aive Pevkur, Alberto Santos Ferro + 14 more
Alexander Kriebitz1\* , Caitlin Corrigan2, Aive Pevkur 3 , Alberto Santos Ferro 4 , Amanda Horzyk 5 , Dirk Brand 6 , Dohee Kim 7 , Dodzi Koku Hattoh 8 , Flavia Massucci 9 , Gilles Fayad 10 , Kamil Strzępek 11 , Laud Ammah 2 , Lavina Ramkissoon 12 , Mariette Awad 13 , Natalia Amasiadi 14 , Nathan C. Walker 15 , Nicole…
Rachel M. Petersen, Rob Tennyson, Tan Bee Ting A/P Tan Boon Huat, Kar Lye Tam + 10 more
Early life environments can have long-lasting impacts on health and fitness, but the evolutionary significance of these effects remains debated. Two major classes of explanations have been proposed: developmental constraints (DC) explanations posit that early life adversity limits optimal development, leading to…
Authors not listed
Molecular mechanisms governing initiation steps of the assembly of thousands of endogenous multi-protein complexes (EMCs) remain incompletely understood. Here, multiple lines of observations are reported reflecting the biological functions-aligned initiation sequence of hybrid assembly pathways (HAPs) of EMCs. HAPs…
Jeroen Vaes, Cecilia Dapor, Federica Meconi, Ermanno Quadrelli + 5 more
In the last 25 years, research on dehumanization-the tendency to perceive others as less than fully human-has spiked and evolved in many ways. In the current review, we will provide an overview of the various methodological and conceptual trends in this research area and introduce a new way of conceptualizing…
Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Stephanie Le + 27 more
Expansion of the glutamine tract (poly-Q) in the protein Huntingtin (HTT) causes the neurodegenerative disorder Huntington’s disease (HD). Emerging evidence suggests that mutant HTT (mHTT) disrupts brain development. To gain mechanistic insights into the neurodevelopmental impact of human mHTT, we engineered induced…
Marcus J. Hamilton
The human niche represents the intersection of biological, ecological, cultural, and technological processes that have co-evolved to shape human adaptation and societal complexity. This paper explores the human niche through the lens of macroecological scaling theory, seeking to define and quantify the dimensions along…
Emily J. Levy, Anna Lee, I. Long’ida Siodi, Emma C. Helmich + 7 more
In many taxa, adverse early-life environments are associated with reduced growth and smaller body size in adulthood. However, in wild primates, we know very little about whether, where, and to what degree trajectories are influenced by early adversity, or which types of early adversity matter most. Here, we use…
George C. Gabriel, Hisato Yagi, Tuantuan Tan, Abha S. Bais + 10 more
Poor neurodevelopment is often observed with congenital heart disease (CHD), especially with mutations in chromatin modifiers. Here analysis of mice with hypoplastic left heart syndrome (HLHS) arising from mutations in Sin3A associated chromatin modifier Sap130, and adhesion protein Pcdha9, revealed neurodevelopmental…
Elizabeth C. Lange, Madison Griffin, Arielle S. Fogel, Elizabeth A. Archie + 2 more
Affiliative social bonds are linked to fitness components in many social mammals. However, despite their importance, little is known about how the tendency to form social bonds develops in young animals, or if the development of social behavior is heritable and thus can evolve. Using four decades of longitudinal…
Bryon Drown, Kevin Jooß, Rafael Melani, Cameron Lloyd-Jones + 2 more
A functional understanding of the human body requires structure-function studies of proteins at scale. The chemical structure of proteins is controlled at the transcriptional, translational, and post-translational levels, creating a variety of products with modulated functions within the cell. The term “proteoform”…
Ricardo A. DeMoya, Rachel E. Forman-Rubinsky, Deon Fontaine, Joseph Shin + 3 more
Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130kDa (Sap130), a protein in the chromatin modifying SIN3A/HDAC1 complex, as a gene contributing to the digenic etiology of HLHS. Here…