13 papers · ranked by Valyu relevance
Yuelin Shi, Dasheng Bi, Janis K. Hesse, Frank F. Lanfranchi + 2 more
A fundamental paradigm in neuroscience is that neurons represent the world through fixed tuning functions, with stable mappings from stimulus features to firing rates1. Here, we report that tuning can instead shift rapidly and coherently across a neural population, enabling a dynamic transition from detecting a broad…
Wataru Suzuki, Keiji Tanaka
Visual expertise in discriminating fine differences among a group of similar objects can be obtained through extensive long-term training. Here we investigated the neural bases of this superior capability. The inferotemporal cortex, located at the final stage along the ventral visual pathway, was a candidate site in…
Charles R E Wilson, David Gaffan, Anna S Mitchell, Mark G Baxter
Disconnection of the frontal lobe from the inferotemporal cortex produces deficits in a number of cognitive tasks that require the application of memory-dependent rules to visual stimuli. The specific regions of frontal cortex that interact with the temporal lobe in performance of these tasks remain undefined. One…
Noritaka Ichiohe, Elena Borra, Kathleen S Rockland
We investigated [1] circuits for object recognition in macaque anterior (TE) and posterior inferotemporal cortex (TEO), using a two-step method for in vivo anatomical imaging. In step 1, red fluorescent tracer was injected into TE to reveal and Pre-target patches of feedforward neurons in TEO. In step 2, these were…
C R E Wilson, M G Baxter, A Easton, D Gaffan
Both frontal-inferotemporal disconnection and fornix transection (Fx) in the monkey impair object-in-place scene learning, a model of human episodic memory. If the contribution of the fornix to scene learning is via interaction with or modulation of frontal-temporal interaction − that is, if they form a unitary system…
Marta Córcoles-Parada, Mar Ubero-Martínez, Richard G. M. Morris, Ricardo Insausti + 2 more
'Ricardo Insausti' 'Mortimer Mishkin' 'Mónica Muñoz-López'] The temporal pole (TP) has been involved in multiple functions from emotional and social behavior, semantic processing, memory, language in humans and epilepsy surgery, to the fronto-temporal neurodegenerative disorder (semantic) dementia. However, the role of…
Mark G Baxter, David Gaffan, Diana A Kyriazis, Anna S Mitchell
Theories of dorsolateral prefrontal cortex (DLPFC) involvement in cognitive function variously emphasize its involvement in rule implementation, cognitive control, or working and/or spatial memory. These theories predict broad effects of DLPFC lesions on tests of visual learning and memory. We evaluated the effects of…
Davide Giampiccolo, Guillaume Herbet, Hugues Duffau
The inferior-fronto-occipital fasciculus (IFOF) is a long-range white matter tract that connects the prefrontal cortex with parietal, posterior temporal and occipital cortices. First identified in the 19th century through the pioneering studies of Mayo and Meynert using blunt dissection, its anatomy and function remain…
M. Muñoz-López, R. Insausti, A. Mohedano-Moriano, M. Mishkin + 1 more
'R. C. Saunders'] Auditory recognition memory in non-human primates differs from recognition memory in other sensory systems. Monkeys learn the rule for visual and tactile delayed matching-to-sample within a few sessions, and then show one-trial recognition memory lasting 10-20 min. In contrast, monkeys require…
Ethan Danielli, Nicholas Simard, Carol A. DeMatteo, Dinesh Kumbhare + 2 more
'Stephan Ulmer' 'Michael D. Noseworthy'] The human brain is an exceptionally complex organ that is comprised of billions of neurons. Therefore, when a traumatic event such as a concussion occurs, somatic, cognitive, behavioral, and sleep impairments are the common outcome. Each concussion is unique in the sense that…
Pedro Aleixo Nogueira, Julia Franco Neiva, Maíra Piani Couto, Marcus Vinicius Giglio + 4 more
The insular cortex is usually hidden underneath the inner surface of the operculum (). Once the dissection of the cortex and U fibers of the frontal, temporal, parietal, and occipital lobes is completed, it is possible to expose the insular cortex by lifting the operculum (; ). To enhance visualization of the white…
Hossein Haghir, Anika Kuckertz, Ling Zhao, Javad Hami + 1 more
'Nicola Palomero-Gallagher'] Neurotransmitters and their receptors are key molecules in information transfer between neurons, thus enabling inter-areal communication. Therefore, multimodal atlases integrating the brain’s cyto- and receptor architecture constitute crucial tools to understand the relationship between its…
K.S.V Angu Bala Ganesh, Payal Panda, Amit H. Makwana, Prarthana Kalerammana Gopalakrishna + 2 more
'Prarthana Kalerammana Gopalakrishna' 'Kandula Prameela Rani' 'Thirupathirao Vishnumukkala'] The amygdala is a complex cellular structure situated centrally in the brain, adjacent to the hippocampus. It is an integral part of the limbic system and is essential for the processing of emotional reactions. The amygdala…