12 papers · ranked by Valyu relevance
Daniel Dadush, Friedrich Eisenbrand, Thomas Rothvoss
Approximate integer programming is the following: For a given convex body $K \subseteq{\mathbb{R}}^n$, either determine whether $K \cap{\mathbb{Z}}^n$ is empty, or find an integer point in the convex body $2\cdot K - c +c$ which is K, scaled by 2 from its center of gravity c. Approximate integer programming can be…
Marcin Briański, Martin Koutecký, Daniel Král’, Kristýna Pekárková + 1 more
An intensive line of research on fixed parameter tractability of integer programming is focused on exploiting the relation between the sparsity of a constraint matrix A and the norm of the elements of its Graver basis. In particular, integer programming is fixed parameter tractable when parameterized by the primal…
Mengzhen Guo, Stefan Grünewald
We present Lpnet, a variant of the widely used Neighbor-net method that approximates pairwise distances between taxa by a circular phylogenetic network. We first apply standard methods to construct a binary phylogenetic tree and then use integer linear programming to compute an optimal circular orderings that agrees…
Frans Zdyb, Julius B. Kirkegaard
Biological image and video analysis is full of discrete decisions: whether an object is present, which multi-hypothesis detections are real, whether two detections are tracking the same object, or whether a cell divides or not. Standard pipelines resolve these locally and in sequence, e.g through non-max suppression…
K. H. Benjamin Leung, Nasrin Yousefi, Timothy C. Y. Chan, Ahmed M. Bayoumi
Putting the 4 components together, a general optimization model can be formulated as follows: maximize f ( x 1 , … , x n ; α 1 , … , α k ) subject to g i ( x 1 , … , x n ; α 1 , … , α k ) ≥ 0 , i = 1 , … , m This optimization model aims to maximize an objective function $f$ with $n$ decision variables $x_{1},…,x_{n}$…
Virgile Andreani, Eric J. South, Mary J. Dunlop
Dense arrangements of binding sites within nucleotide sequences can collectively influence downstream transcription rates or initiate biomolecular interactions. For example, natural promoter regions can harbor many overlapping transcription factor binding sites that influence the rate of transcription initiation.…
Elisabeth Gaar, Markus Sinnl
The discrete -neighbor -center problem (d--CP) is an emerging variant of the classical -center problem which recently got attention in literature. In this problem, we are given a discrete set of points and we need to locate facilities on these points in such a way that the maximum distance between each point where no…
Daniel Molina-Pérez, Edgar Alfredo Portilla-Flores, Efrén Mezura-Montes, Eduardo Vega-Alvarado + 2 more
'Efrén Mezura-Montes' 'Eduardo Vega-Alvarado' 'María Bárbara Calva-Yañez' 'Thomas Stützle'] Mixed integer nonlinear programming (MINLP) addresses optimization problems that involve continuous and discrete/integer decision variables, as well as nonlinear functions. These problems often exhibit multiple discontinuous…
Ahmad Abdi, Gérard Cornuéjols, Bertrand Guenin, Levent Tunçel
A rational number is dyadic if it has a finite binary representation $p/2^k$, where p is an integer and k is a nonnegative integer. Dyadic rationals are important for numerical computations because they have an exact representation in floating-point arithmetic on a computer. A vector is dyadic if all its entries are…
Henri Schmidt, Benjamin J. Raphael
Reconstructing unobserved ancestral states of a phylogenetic tree provides insight into the history of evolving systems and is one of the fundamental problems in phylogenetics. For a fixed phylogenetic tree, the most parsimonious ancestral reconstruction – a solution to the small parsimony problem – can be efficiently…
Pouya Ahadi, Balabhaskar Balasundaram, Juan S. Borrero, Charles Chen
In this study, we address the mate selection problem in the hybridization stage of a breeding pipeline, which constitutes the multi-objective breeding goal key to the performance of a variety development program. The solution framework we formulate seeks to ensure that individuals with the most desirable genomic…
Berhanu Belay, Adane Abebaw, Omar A. Alzubi
This manuscript presents a technique for solving a multiple-objective probabilistic fractional programming problem with discrete random variables. A multiple-objective probabilistic mathematical model is constructed with fractional objectives. In the model, some parameters of coefficients and right hand side parameters…