13 papers · ranked by Valyu relevance
Pratik Jaluria, Konstantinos Konstantopoulos, Michael Betenbaugh, Joseph Shiloach
'Joseph Shiloach'] With advances in robotics, computational capabilities, and the fabrication of high quality glass slides coinciding with increased genomic information being available on public databases, microarray technology is increasingly being used in laboratories around the world. In fact, fields as varied as…
Greg Gibson
Microarrays can survey genome-wide expression patterns. Not only can these gene expression profiles be used to identify a few genes of interest, they are now being creatively applied for hypothesis generation and testing
Rebecca Jonczyk, Tracy Kurth, Antonina Lavrentieva, Johanna-Gabriela Walter + 3 more
'Johanna-Gabriela Walter' 'Thomas Scheper' 'Frank Stahl' 'Holger Erfle'] Living cell microarrays are a highly efficient cellular screening system. Due to the low number of cells required per spot, cell microarrays enable the use of primary and stem cells and provide resolution close to the single-cell level. Apart from…
D. A. Gryadunov, B. L. Shaskolskiy, T. V. Nasedkina, A. Yu. Rubina + 1 more
'A. S. Zasedatelev'] Biological microarrays (biochips) are analytical tools that can be used to implement complex integrative genomic and proteomic approaches to the solution of problems of personalized medicine (e.g., patient examination in order to reveal the disease long before the manifestation of clinical…
Manish Biyani, Takanori Ichiki, Massimo Negrini
Advances in lithographic approaches to fabricating bio-microarrays have been extensively explored over the last two decades. However, the need for pattern flexibility, a high density, a high resolution, affordability and on-demand fabrication is promoting the development of unconventional routes for microarray…
Chandra K. Dixit, Gerson R. Aguirre
Microfluidic-based micromosaic technology has allowed the pattering of recognition elements in restricted micrometer scale areas with high precision. This controlled patterning enabled the development of highly multiplexed arrays multiple analyte detection. This arraying technology was first introduced in the beginning…
G. M. Aparna, Kishore K. R. Tetala, Marshall Williams
Microarrays are one of the trailblazing technologies of the last two decades and have displayed their importance in all the associated fields of biology. They are widely explored to screen, identify, and gain insights on the characteristics traits of biomolecules (individually or in complex solutions). A wide variety…
Ursula Sauer, Eiichi Tamiya, Yuji Murakami, Tatsuro Endo + 1 more
"Mun'delanji Vestergaard"] Protein microarrays represent a powerful technology with the potential to serve as tools for the detection of a broad range of analytes in numerous applications such as diagnostics, drug development, food safety, and environmental monitoring. Key features of analytical protein microarrays…
Richard JD Rouse, Katrine Field, Jennifer Lapira, Allen Lee + 5 more
'Ivan Wick' 'Colleen Eckhardt' 'C Ramana Bhasker' 'Laura Soverchia' 'Gary Hardiman'] Background Successful microarray experimentation requires a complex interplay between the slide chemistry, the printing pins, the nucleic acid probes and targets, and the hybridization milieu. Optimization of these parameters and a…
Tim Lenoir, Eric Giannella
The network model of innovation widely adopted among researchers in the economics of science and technology posits relatively porous boundaries between firms and academic research programs and a bi-directional flow of inventions, personnel, and tacit knowledge between sites of university and industry innovation.…
E. V. Dubrovin, G. V. Presnova, M. Yu. Rubtsova, A. M. Egorov + 2 more
'V. G. Grigorenko' 'I. V. Yaminsky'] Oligonucleotide microarrays are considered today to be one of the most efficient methods of gene diagnostics. The capability of atomic force microscopy (AFM) to characterize the three-dimensional morphology of single molecules on a surface allows one to use it as an effective tool…
Alexander Asanov, Angélica Zepeda, Luis Vaca
We have developed a novel microarray technology based on total internal reflection fluorescence (TIRF) in combination with DNA and protein bioassays immobilized at the TIRF surface. Unlike conventional microarrays that exhibit reduced signal-to-background ratio, require several stages of incubation, rinsing and…
Kentaro Nishi, Shin-Ichiro Isobe, Yun Zhu, Ryoiti Kiyama + 1 more
'Arun Bhunia'] We summarize here the recent progress in fluorescence-based bioassays for the detection and evaluation of food materials by focusing on fluorescent dyes used in bioassays and applications of these assays for food safety, quality and efficacy. Fluorescent dyes have been used in various bioassays, such as…