15 papers · ranked by Valyu relevance
Marie Engelene J. Obien, Kosmas Deligkaris, Torsten Bullmann, Douglas J. Bakkum + 1 more
'Douglas J. Bakkum' 'Urs Frey'] Microelectrode arrays and microprobes have been widely utilized to measure neuronal activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate neurons at multiple sites simultaneously. However, unlike the single-cell or single-channel resolution of…
Gerard O’Leary, Iouri Khramtsov, Rakshith Ramesh, Aidan Perez-Ignacio + 5 more
Bioelectronic interfaces have the potential to revolutionize the treatment of medical disorders and augment physiology. Implantable devices such as pacemakers and deep brain stimulators have already been deployed to control activity in diseases including Parkinson’s disease and epilepsy. These devices typically operate…
Katarzyna M. Szostak, Laszlo Grand, Timothy G. Constandinou
Implantable neural interfaces for central nervous system research have been designed with wire, polymer, or micromachining technologies over the past 70 years. Research on biocompatible materials, ideal probe shapes, and insertion methods has resulted in building more and more capable neural interfaces. Although the…
Elton Ho, Mark Hettick, Demetrios Papageorgiou, Adam J. Poole + 7 more
Progress toward the development of brain–computer interfaces has signaled the potential to restore, replace, or augment lost or impaired neurological function in a variety of disease states. Existing brain–computer interfaces rely on invasive surgical procedures or brain-penetrating electrodes, which limit addressable…
Cat-Vu H. Bui, Neethu Maliakal, Hasan Ulusan, Andreas Hierlemann + 2 more
'Fernando Cardes' 'Attila Kaszás'] Electrode designs and materials have become an increasingly important performance driver for microelectrode arrays, which are among the essential tools for cellular electrophysiology. Ongoing works have continuously innovated over a diverse range of electrode shapes, sizes, and…
Pingyu Wang, Eric G. Wu, Hasan Uluşan, A.J. Phillips + 10 more
Silicon-based planar microelectronics is a powerful tool for scalably recording and modulating neural activity at high spatiotemporal resolution, but it remains challenging to target neural structures in three dimensions (3D). We present a method for directly fabricating 3D arrays of tissue-penetrating microelectrodes…
Kejun Xie, Shaomin Zhang, Shurong Dong, Shijian Li + 6 more
'Kedi Xu' 'Wanke Chen' 'Wei guo' 'Jikui Luo' 'Zhaohui Wu'] In this paper, we present a portable wireless electrocorticography (ECoG) system. It uses a high resolution 32-channel flexible ECoG electrodes array to collect electrical signals of brain activities and to stimulate the lesions. Electronic circuits are…
Jeffrey R. Naughton, Timothy Connolly, Juan A. Varela, Jaclyn Lundberg + 4 more
'Jaclyn Lundberg' 'Michael J. Burns' 'Thomas C. Chiles' 'John P. Christianson' 'Michael J. Naughton'] Recent progress in the study of the brain has been greatly facilitated by the development of new tools capable of minimally-invasive, robust coupling to neuronal assemblies. Two prominent examples are the…
Huiqing Zhao, Ruping Liu, Huiling Zhang, Peng Cao + 3 more
'Ye Li' 'Joseph Pancrazio'] Neural microelectrode is the important bridge of information exchange between the human body and machines. By recording and transmitting nerve signals with electrodes, people can control the external machines. At the same time, using electrodes to electrically stimulate nerve tissue, people…
Chih-Wei Chang, Jin-Chern Chiou
This paper presents the design and implementation of an integrated wireless microsystem platform that provides the possibility to support versatile implantable neural sensing devices in free laboratory rats. Inductive coupled coils with low dropout regulator design allows true long-term recording without limitation of…
Flávio Afonso Gonçalves Mourão, Leonardo de Oliveira Guarnieri, Paulo Aparecido Amaral Júnior, Vinícius Rezende Carvalho + 2 more
Electrophysiological recordings lead amongst the techniques that aim to investigate the dynamics of neural activity sampled from large neural ensembles. However, the financial costs associated with the state-of-the-art technology used to manufacture probes and multi-channel recording systems make these experiments…
Mihaly Kollo, Romeo R Racz, Mina-Elraheb S Hanna, Abdulmalik M Obaid + 7 more
Mammalian brains consist of 10s of millions to 100s of billions of neurons operating at millisecond time scales, of which current recording techniques only capture a tiny fraction. Recording techniques capable of sampling neural activity at such temporal resolution have been difficult to scale: The most intensively…
Horacio Londoño‐Ramírez, Xiaohua Huang, Jordi Cools, Anna Chrzanowska + 8 more
'Anna Chrzanowska' 'Clément Brunner' 'Marco Ballini' 'Luis Hoffman' 'Soeren Steudel' 'Cédric Rolin' 'Carolina Mora Lopez' 'Jan Genoe' 'Sebastian Haesler'] Title: Abstract Electrode grids are used in neuroscience research and clinical practice to record electrical activity from the surface of the brain. However…
Romeo R Racz, Mihaly Kollo, Gabriella Racz, Ciprian Bulz + 9 more
High signal-to-noise, scalable and minimally invasive recording and stimulation of the nervous system in intact animals is of fundamental importance to advance the understanding of brain function. Extracellular electrodes are among the most powerful tools capable of interfacing with large neuronal populations^1–3^.…
Mihály Vöröslakos, Peter C. Petersen, Balázs Vöröslakos, György Buzsáki
High-yield electrophysiological extracellular recording in freely moving rodents provides a unique window into the temporal dynamics of neural circuits. Recording from unrestrained animals is critical to investigate brain activity during natural behaviors. The use and implantation of high-channel-count silicon probes…