10 papers · ranked by Valyu relevance
Ana Lúcia Leitão, Francisco J Enguita
The evolution of molecular visualization software represents a pivotal yet often underappreciated dimension of computational structural biology and bioinformatics. As the scale and complexity of structural datasets increase, spanning from cryo-electron microscopy reconstructions to proteome-wide AI-predicted models…
Priyanka Bhutada, Nitin Goyal, Tatsam K. Lakhankiya, Sai D. Narahari + 8 more
Artificial Intelligence (AI) frameworks for automating scientific research have shown strong performance on benchmarks, but their utility for real-world industrial research remains insufficiently characterized. Extending the analysis presented in the first paper of this series, we evaluated the same five advanced AI…
Lianne Gahan, Adélaïde Raguin, Partho Sakha De
Lignin’s complex and highly branched architecture plays a critical role in biomass utilisation. Yet, unravelling the intricate relation between lignin’s measurable structural features and the underlying biosynthesis dynamics remains a major challenge. This difficulty stems from the variability in monolignol and bond…
Eliezer Masliah
How transient neural representations become integrated and stable enough to function as internal neural models remains incompletely understood. Grounded in efficient coding, Bayesian and predictive frameworks, recurrent and attractor dynamics, neural state-space models, and systems neuroscience, the Principle of…
Alaksh Choudhury, Stanislas Thiriet-Rupert, Zoya Dixit, Melanie Magnan + 3 more
Although biofilms represent the dominant bacterial lifestyle and are major contributors to recalcitrant, treatment-resistant infections, their evolutionary dynamics at the individual lineage resolution remain poorly understood. We combine DNA barcoding-mediated lineage tracking and spatial sampling of > 100,000…
Seiya Nishikawa, Satoshi Kuwana, Gen Honda, Hidenori Hashimura + 2 more
We investigate the mechanical principles underlying fruiting body morphogenesis in Dictyostelium discoideum. Quantitative shape analysis based on the Young–Laplace law, together with AFM indentation measurements, indicate surface tension as the dominant tissue-scale force acting on the culminating fruiting body. Based…
Xu Lin, Meisheng Han, Haolin Ju, Hengyuan Hu + 6 more
Title: Highlights 1. Systematically elucidates the physical (transmembrane migration-induced volume imbalance), chemical (inactivation of active species), and interfacial (electrode degradation, hydrogen/oxygen evolution) origins of capacity fade in redox flow batteries. 2. Summarizes recovery approaches from physical…
Xiaoyue Hu, Yuhao Ma, Ruixing Ming, Heping Zhang + 1 more
Identifying essential biomarkers remains a core challenge in elucidating the pathogenic mechanisms and achieving precise diagnosis of complex diseases. Deep neural networks offer immense predictive power, yet their lack of interpretability severely limits downstream biological insight. Here, we introduce DeepVaris, an…
Junjie Yao, Zhongxu Li, Cuiping Wang, Junyu Wu + 3 more
A motion control strategy based on multi-source heterogeneous motion information fusion and motion decoupling parallel washout algorithm (WA) is proposed for the control of a rehabilitation robot designed for stroke-related balance disorders. The robot features a serial-parallel hybrid structure and humanoid gait…
Peter F. Pelz, Tobias Meck
For nearly a century, the physical origin of metabolic scaling has remained unresolved: metabolism is proportional to body mass in small organisms but follows Kleiber’s three-quarter-power law in larger animals. We derive both regimes from the Metabolic Holon (MH), a locally optimized capillary–tissue oxygen-supply…