Search · four archives
Search · four archives
12 papers · ranked by Valyu relevance
Michael T. M. Emmerich, André H. Deutz
In almost no other field of computer science, the idea of using bio-inspired search paradigms has been so useful as in solving multiobjective optimization problems. The idea of using a population of search agents that collectively approximate the Pareto front resonates well with processes in natural evolution, immune…
Wan Liang Wang, Weikun Li, Yu Le Wang
Balancing convergence and diversity has become a key point especially in many-objective optimization where the large numbers of objectives pose many challenges to the evolutionary algorithms. In this paper, an opposition-based evolutionary algorithm with the adaptive clustering mechanism is proposed for solving the…
Zhiming Song, Maocai Wang, Guangming Dai, Massimiliano Vasile
As is known, the Pareto set of a continuous multiobjective optimization problem with m objective functions is a piecewise continuous (m − 1)-dimensional manifold in the decision space under some mild conditions. However, how to utilize the regularity to design multiobjective optimization algorithms has become the…
Kaifeng Yang, Li Mu, Dongdong Yang, Feng Zou + 2 more
'Qiaoyong Jiang'] A novel hybrid multiobjective algorithm is presented in this paper, which combines a new multiobjective estimation of distribution algorithm, an efficient local searcher and ε-dominance. Besides, two multiobjective problems with variable linkages strictly based on manifold distribution are proposed.…
Ke Bao, Wei Fang, Yourong Ding
Although the integrated model has good convergence ability, it is difficult to solve the multimodal problem and noisy problem due to the lack of uncertainty evaluation. Radial basis function model performs best for different degrees of nonlinear problems with small-scale and noisy training datasets but is insensitive…
Sergio Garcia, Cong Trinh
A large space of chemicals with broad industrial and consumer applications could be synthesized by engineered microbial biocatalysts. However, the current strain optimization process is prohibitively laborious and costly to produce one target chemical and often requires new engineering efforts to produce new molecules.…
Jiao Shi, Maoguo Gong, Wenping Ma, Licheng Jiao
How to maintain the population diversity is an important issue in designing a multiobjective evolutionary algorithm. This paper presents an enhanced nondominated neighbor-based immune algorithm in which a multipopulation coevolutionary strategy is introduced for improving the population diversity. In the proposed…
Hao Chen, Weikun Li, Weicheng Cui
Nature-inspired computing has attracted huge attention since its origin, especially in the field of multiobjective optimization. This paper proposes a disruption-based multiobjective equilibrium optimization algorithm (DMOEOA). A novel mutation operator named layered disruption method is integrated into the proposed…
Lu Hong, Tanja Kortemme
With recent methodological advances in the field of computational protein design, in particular those based on deep learning, there is an increasing need for frameworks that allow for coherent, direct integration of different models and objective functions into the generative design process. Here we demonstrate how…
David Bassen, Michael Vilkhovoy, Mason Minot, Jonathan T Butcher + 1 more
Ensemble modeling is a well established approach for obtaining robust predictions and for simulating course grained population behavior in deterministic mathematical models. In this study, we present a multiobjective based technique to estimate model ensembles, the Pareto Optimal Ensemble Technique in the Julia…
Álvaro Rubio-Largo, Miguel A. Vega-Rodríguez
The alignment among three or more nucleotides/amino-acids sequences at the same time is known as Multiple Sequence Alignment (MSA), an NP-hard optimization problem. The time complexity of finding an optimal alignment raises exponentially when the number of sequences to align increases. In this work, we deal with a…
Alexander Lalejini, Emily Dolson, Anya E. Vostinar, Luis Zaman
Directed microbial evolution harnesses evolutionary processes in the laboratory to construct microorganisms with enhanced or novel functional traits. Attempting to direct evolutionary processes for applied goals is fundamental to evolutionary computation, which harnesses the principles of Darwinian evolution as a…