11 papers · ranked by Valyu relevance
Jie Wang, Liangjian Cai, Jinzhu Peng, Yuheng Jia
Since real-world data sets usually contain large instances, it is meaningful to develop efficient and effective multiple instance learning (MIL) algorithm. As a learning paradigm, MIL is different from traditional supervised learning that handles the classification of bags comprising unlabeled instances. In this paper…
Christian Hallgrimson, Y. Lydia Li, Claire A. Shou, Ben Cardoen + 5 more
Single-molecule localization microscopy (SMLM) achieves nanoscale imaging of complex protein structures in the cell. However, the ability to capture structural variability across cell conditions (cell lines, gene expression, treatment) from 3D point cloud SMLM data remains limited. We present siMILe, a…
Christian Hallgrimson, Y. Lydia Li, Ben Cardoen, John Lim + 4 more
Single-molecule localization microscopy (SMLM) achieves nanoscale imaging of complex protein structures in the cell. However, the ability to capture structural variability across cell conditions (cell lines, gene expression, treatment) from 3D point cloud SMLM data remains limited. We present siMILe, a novel…
Michael Widrich, Bernhard Schäfl, Milena Pavlović, Geir Kjetil Sandve + 3 more
High-throughput immunosequencing allows re-constructing the immune repertoire of an individual, which is an exceptional opportunity for new immunotherapies, immunodiagnostics, and vaccine design. Such immune repertoires are shaped by past and current immune events, for example infection and disease, and thus record an…
Dan Liu, Francesca Young, David L Robertson, Ke Yuan
Predicting virus-host associations is essential to determine the specific host species that viruses interact with, and discover if new viruses infect humans and animals. Currently, the host of the majority of viruses is unknown, particularly in microbiomes. To address this challenge, we introduce EvoMIL, a deep…
Christian Hallgrimson, Y. Lydia Li, Claire A. Shou, Ben Cardoen + 5 more
Single-molecule localization microscopy (SMLM) achieves nanoscale imaging of complex protein structures in the cell. However, the ability to capture structural variability across cell conditions (cell lines, gene expression, treatment) from 3D point cloud SMLM data remains limited. We present siMILe, a weakly…
Zhendong Zhao, Gang Fu, Sheng Liu, Khaled M Elokely + 3 more
'Robert J Doerksen' 'Yixin Chen' 'Dawn E Wilkins'] Background In drug discovery and development, it is crucial to determine which conformers (instances) of a given molecule are responsible for its observed biological activity and at the same time to recognize the most representative subset of features (molecular…
Yonghui Xu, Huaqing Min, Qingyao Wu, Hengjie Song + 1 more
Multi-Instance (MI) learning has been proven to be effective for the genome-wide protein function prediction problems where each training example is associated with multiple instances. Many studies in this literature attempted to find an appropriate Multi-Instance Learning (MIL) method for genome-wide protein function…
Anastasia Litinetskaya, Soroor Hediyeh-zadeh, Amir Ali Moinfar, Mohammad Lotfollahi + 1 more
To deliver clinically relevant insights from large patient cohorts profiled with single-cell technologies, a key challenge is to relate sample-level and single-cell measurements. We present MultiMIL, a deep learning framework that applies attention-based multiple-instance learning for phenotype prediction and cell…
Bita Ghasemkhani, Ozlem Varliklar, Yunus Dogan, Semih Utku + 6 more
Simple Summary This study addresses the classification task in animal science, which helps organize and analyze complex data, essential for making informed decisions. It introduces Federated Multi-Label Learning (FMLL), a novel approach combining federated learning principles with a multi-label learning technique.…
Mert Bal, M. Fatih Amasyali, Hayri Sever, Guven Kose + 1 more
The importance of the decision support systems is increasingly supporting the decision making process in cases of uncertainty and the lack of information and they are widely used in various fields like engineering, finance, medicine, and so forth, Medical decision support systems help the healthcare personnel to select…