8 papers · ranked by Valyu relevance
Mitja Briscik, Gabriele Tazza, László Vidács, Marie-Agnès Dillies + 1 more
'Sébastien Déjean'] Background Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel learning (MKL) has shown to be a flexible and valid…
Kosuke Yoshida, Junichiro Yoshimoto, Kenji Doya
Background Advance in high-throughput technologies in genomics, transcriptomics, and metabolomics has created demand for bioinformatics tools to integrate high-dimensional data from different sources. Canonical correlation analysis (CCA) is a statistical tool for finding linear associations between different types of…
Wenjia Niu, Kewen Xia, Baokai Zu, Jianchuan Bai
Unlike Support Vector Machine (SVM), Multiple Kernel Learning (MKL) allows datasets to be free to choose the useful kernels based on their distribution characteristics rather than a precise one. It has been shown in the literature that MKL holds superior recognition accuracy compared with SVM, however, at the expense…
Longlong Liao, Kenli Li, Keqin Li, Canqun Yang + 1 more
Background While there are a large number of bioinformatics datasets for clustering, many of them are incomplete, i.e., missing attribute values in some data samples needed by clustering algorithms. A variety of clustering algorithms have been proposed in the past years, but they usually are limited to cluster on the…
Christopher M. Wilson, Kaiqiao Li, Xiaoqing Yu, Pei-Fen Kuan + 1 more
'Xuefeng Wang'] Background Advances in medical technology have allowed for customized prognosis, diagnosis, and treatment regimens that utilize multiple heterogeneous data sources. Multiple kernel learning (MKL) is well suited for the integration of multiple high throughput data sources. MKL remains to be…
Meshal Shutaywi, Nezamoddin N. Kachouie, Antonio M. Scarfone
Grouping the objects based on their similarities is an important common task in machine learning applications. Many clustering methods have been developed, among them k-means based clustering methods have been broadly used and several extensions have been developed to improve the original k-means clustering method such…
Tom Dupré la Tour, Michael Eickenberg, Anwar O. Nunez-Elizalde, Jack L. Gallant
'Jack L. Gallant'] Encoding models provide a powerful framework to identify the information represented in brain recordings. In this framework, a stimulus representation is expressed within a feature space and is used in a regularized linear regression to predict brain activity. To account for a potential…
Esteban Vegas, Josep M. Oller, Ferran Reverter
Background Pathway expression is multivariate in nature. Thus, from a statistical perspective, to detect differentially expressed pathways between two conditions, methods for inferring differences between mean vectors need to be applied. Maximum mean discrepancy (MMD) is a statistical test to determine whether two…