9 papers · ranked by Valyu relevance
Rob Patro, Siddhant Bharti, Prajwal Singhania, Rakrish Dhakal + 2 more
The FASTQ file format is the lingua franca of primary data distribution and processing across most of bioinformatics. Over time, the compression, storage, transmission, and decompression of gzip compressed fastq.gz files has become a substantial scalability bottleneck in the modern world of fast and massively parallel…
Pavo Orepic, Wilson Truccolo, Sydney S. Cash, Anne-Lise Giraud + 1 more
Traditional models of speech perception posit that neural activity sequentially encodes speech through a hierarchy of cognitive processes, from early representations of acoustic and phonetic features to late semantic encoding. Yet the mechanisms by which neural representations are transformed across the speech…
Amie Fairs, Amandine Michelas, Sophie Dufour, Kristof Strijkers
The temporal dynamics by which linguistic information becomes available is one of the key properties to understand how language is organised in the brain. An unresolved debate between different brain language models is whether words, the building blocks of language, are activated in a sequential or parallel manner. In…
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Bayesian optimization (BO) has become increasingly important for experimental optimization across scientific domains, yet implementing BO pipelines requires significant programming expertise and familiarity with specialized frameworks. This creates a barrier for domain experts who could benefit from BO but lack the…
Ryan M.C. Law, Matthew A. Lambon Ralph, Olaf Hauk
How the brain constructs meaning from individual words and phrases is a fundamental question for research in semantic cognition, language and their disorders. These two aspects of meaning are traditionally studied separately, resulting in two large, multi-method literatures, which we sought to bring together in this…
Carlo Y. Meloni, Chundra A. Cathcart, Erik J. Ringen, Jessica K. Ivani + 1 more
We examine the syntax-semantics interface in clause linkage using a cross-linguistic sample of nearly 700 constructions from Indo-European, Sino-Tibetan, and Tupí-Guaraní. To evaluate predictions from the Interclausal Relations Hierarchy, we model the phylogenetic dynamics of how semantic relations influence the degree…
Ryan Law, Liina Pylkkänen
In the neurobiology of language, a fundamental challenge is deconfounding syntax from semantics. Changes in syntactic structure usually correlate with changes in meaning. We approached this challenge from a new angle. We deployed word lists, which are usually the unstructured control in studies of syntax, as both the…
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Protein conformational landscapes contain the functionally relevant information useful for understanding biological processes. Mapping out conformational landscapes provides valuable insights into protein behaviors and biological phenomena, and has relevance to therapeutic design. While experimental structural biology…
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Step-by-step thinking is essential in all domains of chemical sciences and engineering. While machine learning tools are broadly used, algorithms that automate reasoning are far less common. We elaborate on seven categories of human reasoning activities and connect each to applications in chemical science and…