15 papers · ranked by Valyu relevance
Gina F. Humphreys, Rebecca L. Jackson, Matthew A. Lambon Ralph
The parietal cortex (PC) is implicated in a confusing myriad of different cognitive processes/tasks. Consequently, understanding the nature and organisation of the core underlying neurocomputations is challenging. According to the Parietal Unified Connectivity-biased Computation (PUCC) model two properties underpin PC…
Karoline Hovde, Michele Gianatti, Menno P. Witter, Jonathan R. Whitlock
The posterior parietal cortex (PPC) is a multifaceted region of cortex, contributing to several cognitive processes including sensorimotor integration and spatial navigation. Although recent years have seen a considerable rise in the use of rodents, particularly mice, to investigate PPC and related networks, a coherent…
Olga I. Ivashkina, Anna M. Gruzdeva, Marina A. Roshchina, Ksenia A. Toropova + 1 more
The parietal cortex in rodents has an integrative function and participates in sensory and spatial processing, movement planning and decision-making. However, much less is known about its functions in associative memory processing. Here using Fos immunohistochemical mapping of neuronal activity and two-photon imaging…
Julie J Lee, Michael Krumin, Kenneth D Harris, Matteo Carandini
Parietal cortex is implicated in a variety of behavioral processes, but it is unknown whether and how individual neurons participate in multiple tasks. We trained head-fixed mice to perform two visual decision tasks involving a steering wheel or a virtual T-maze, and recorded from the same parietal neurons during the…
Leigh-Anne Dell, Giorgio M. Innocenti, Claus C. Hilgetag, Paul R. Manger
The present study describes the ipsilateral and contralateral cortico-cortical and cortico-thalamic connectivity of the parietal visual areas PPc and PPr in the ferret using standard anatomical tract-tracing methods. The two divisions of posterior parietal cortex of the ferret are strongly interconnected, however area…
Anup Das, Vinod Menon
Hippocampus-parietal cortex circuits are thought to play a crucial role in memory and attention, but their neural basis remains poorly understood. We employed intracranial EEG from 96 participants (51 females) to investigate the neurophysiological underpinning of these circuits across three memory tasks spanning verbal…
Eric Avila, Kaushik J Lakshminarasimhan, Gregory C DeAngelis, Dora E Angelaki
Neurons in the macaque posterior parietal cortex are known to encode the direction of self-motion. But do they also encode one’s speed? To test this, we performed neural recordings from area 7a while monkeys were passively translated or rotated at various speeds. Visual stimuli were delivered as optic flow fields and…
Roberto Caminiti, Gabriel Girard, Alexandra Battaglia-Mayer, Elena Borra + 3 more
In macaque monkeys, dorsal intraparietal areas are involved in several daily visuo-motor actions. However, their border and sources of cortical afferents remain loosely defined. Through a retrograde tracer and MRI diffusion-based tractography study here we show a complex organization of the dorsal bank of the IPS…
Anna Williams, Patricia Hoyos, Ruggaya Musa, Jesse Gomez
The folding of the cortical sheet within the human brain is related to its functional organization at the level of major sulci and gyri. Yet how smaller folding features hidden within the two thirds of cortex buried in sulci may relate to functional specialization of the cortex is not clear. Using human visual cortex…
Ahmad Beyh, Flavio Dell’Acqua, Carlo Sestieri, Massimo Caulo + 6 more
Spatial configuration learning depends on the parahippocampal place area (PPA), a functionally heterogenous area which current visuo-spatial processing models place downstream from parietal cortex and area V4 of early visual cortex (EVC). Here, we present evidence for the medial occipital longitudinal tract (MOLT), a…
Rune N. Rasmussen, Akihiro Matsumoto, Simon Arvin, Keisuke Yonehara
Locomotion creates various patterns of optic flow on the retina, which provide the observer with information about their movement relative to the environment. However, it is unclear how these optic flow patterns are encoded by the cortex. Here we use two-photon calcium imaging in awake mice to systematically map…
Mathilda Froesel, Simon Clavagnier, Quentin Goudrad, Qi Zhu + 2 more
The pulvinar, the largest nucleus of the thalamus, is functionally heterogeneous and involved in multiple cognitive functions. It has been proposed to act as a functional hub of cortical processes due to its extensive reciprocal connectivity with the cortex. However, its role in cognition is not fully understood yet.…
James C. Pang, Peter A. Robinson, Kevin M. Aquino, Priscila T. Levi + 14 more
The mammalian brain is comprised of anatomically and functionally distinct regions. Substantial work over the past century has pursued construction of ever-more accurate maps of regional boundaries, using either expert judgement or data-driven clustering of functional, connectional, and/or architectonic properties.…
Ting Xu, Arnaud Falchier, Elinor L. Sullivan, Gary Linn + 14 more
Complementing longstanding traditions centered around histology, functional magnetic resonance imaging approaches are rapidly maturing in their ability to delineate brain areal organization at the macroscale. In particular, automated approaches focused on the detection of gradient-based boundaries in functional…
Anika Wuestefeld, Hannah Baumeister, Jenna N. Adams, Robin de Flores + 35 more
The medial temporal lobe (MTL) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as Alzheimer’s disease neurofibrillary tau tangles. The MTL cortex is composed of several subregions which differ in their functional and cytoarchitectonic…