11 papers · ranked by Valyu relevance
Tiffany A. Carther-Krone, Jonathan J. Marotta, Mariagrazia Benassi
Humans have the remarkable ability to efficiently group elements of a scene together to form a global whole. However, cross-cultural comparisons show that East Asian individuals process scenes more globally than White individuals. This experiment presents new insights into global processing, revealing the relative…
Trygve E. Bakken, Cindy T.J. van Velthoven, Vilas Menon, Rebecca D. Hodge + 24 more
Abundant anatomical and physiological evidence supports the presence of at least three distinct types of relay glutamatergic neurons in the primate dorsal lateral geniculate nucleus (dLGN) of the thalamus, the brain region that conveys visual information from the retina to the primary visual cortex. Relay neuron…
Naranbat Nasanbuyan, Masahide Yoshida, Yuki Takayanagi, Keiichi Itoi + 1 more
Oxytocin (OXT)- and arginine vasopressin (AVP)-synthesizing neurons are traditionally classified into magnocellular and parvocellular types based on their projection targets. However, molecular markers that reliably distinguish these neuronal subtypes across hypothalamic regions remain undefined. Recent single-cell…
Eastman M. Lewis, Genevieve L. Stein-O’Brien, Alejandra V. Patino, Romain Nardou + 9 more
Parallel processing circuits are thought to dramatically expand the network capabilities of the nervous system. Magnocellular and parvocellular oxytocin neurons have been proposed to subserve two parallel streams of social information processing, which allow a single molecule to encode a diverse array of ethologically…
Akito Otubo, Sho Maejima, Takumi Oti, Keita Satoh + 4 more
Translational research often requires the testing of experimental therapies in primates, but research in non-human primates is now stringently controlled by law around the world. Tissues fixed in formaldehyde without glutaraldehyde have been thought to be inappropriate for use in electron microscopic analysis…
Hitomi Matsuno, Moeko Kudoh, Akiya Watakabe, Tetsuo Yamamori + 3 more
'Ryuichi Shigemoto' 'Soichi Nagao' 'Manuel S. Malmierca'] Adaptations of vestibulo-ocular and optokinetic response eye movements have been studied as an experimental model of cerebellum-dependent motor learning. Several previous physiological and pharmacological studies have consistently suggested that the cerebellar…
Salla Mattola, Satu Hakanen, Sami Salminen, Vesa Aho + 5 more
'Teemu O. Ihalainen' 'Michael Kann' 'Maija Vihinen-Ranta' 'Giorgio Gallinella'] Parvoviruses are small single-stranded (ss) DNA viruses, which replicate in the nucleoplasm and affect both the structure and function of the nucleus. The nuclear stage of the parvovirus life cycle starts at the nuclear entry of incoming…
Lenka Horníková, Kateřina Bruštíková, Sandra Huérfano, Jitka Forstová + 2 more
'Jitka Forstová' 'Natacha Gaillard' 'Ashwani Sharma'] The nuclear lamina is the main component of the nuclear cytoskeleton that maintains the integrity of the nucleus. However, it represents a natural barrier for viruses replicating in the cell nucleus. The lamina blocks viruses from being trafficked to the nucleus for…
Abigail Kimball, Wanyi Huang, Rui Xu, Melanie Key + 2 more
During its asexual cycle, Cryptosporidium parvum (C. parvum) amplifies through three rounds of nuclear division before undergoing cytokinesis to form infectious merozoites. However, chromosome organization and segregation during nuclear division remain unstudied. Here, we visualized H3-histones, including the…
Vanessa Baratta, Jason Own, Chiara Di Renzo, Jenna Ollodart + 2 more
'John P. Geibel' 'Maria Barahona'] The stomach has unique embryologic and anatomic properties, making the study of the parietal cell technically challenging. Numerous individuals have devoted decades of research to unraveling the pathophysiological basis of this cell type. Here, we perform a scoping review of novel in…
Katarzyna Pawlikiewicz, Agnieszka Strzałka, Michał Majkowski, Julia Duława-Kobeluszczyk + 2 more
ParB is long established chromosome segregation protein in bacteria. Due to the recently demonstrated CTPase activity of ParB, formation of its nucleoprotein complexes was unrevealed. ParB homodimers bound to CTP are loaded onto DNA at parS sites, where they recruit condensin (SMC), thereby facilitating chromosome…