14 papers · ranked by Valyu relevance
Karen Dryden-Palmer, Whitney B. Berta, Christopher S. Parshuram
Background Designing implementation programs that effectively integrate complex healthcare innovations into complex settings is a fundamental aspect of knowledge translation. We describe the development of a conceptually grounded implementation program for a complex healthcare innovation and its subsequent application…
Sean Paul Teeling, Carmel Davies, Marlize Barnard, Laserina O’Connor + 21 more
'Alice Coffey' 'Veronica Lambert' 'Martin McNamara' 'Dympna Tuohy' 'Timothy Frawley' 'Catherine Redmond' 'Suja Somanadhan' 'Mary Casey' 'Yvonne Corcoran' 'Owen Doody' 'Denise O’Brien' 'Maria Noonan' 'Rita Smith' 'Carmel Bradshaw' 'Sylvia Murphy' 'Liz Dore' 'Rosemary Lyons' 'Máire McGeehan' 'Anne Gallen' 'Florian…
Renée V.H. IJzerman, Rosalie van der Vaart, Linda D. Breeman, Karin Arkenbout + 5 more
'Karin Arkenbout' 'Mike Keesman' 'Roderik A. Kraaijenhagen' 'Andrea W.M. Evers' 'Wilma J.M. Scholte op Reimer' 'Veronica R. Janssen'] Background The number of complex eHealth interventions has increased considerably. Despite available implementation theory outlining well-designed strategies, implementing complex…
Sarah Scruton, Grace Warner, Cynthia Kendell, Kathryn Pfaff + 5 more
'Kelli Stajduhar' 'Linda Patrick' 'Carren Dujela' 'Faith Fauteux' 'Robin Urquhart'] Background As the Canadian population ages and the prevalence of chronic illnesses increases, delivering high-quality care to individuals with advanced life limiting illnesses becomes more challenging. Community-based navigation…
Eunice Mercado-Lara, Greg Tananbaum, Erin C. McKiernan
The Open Research Funders Group (ORFG) has been instrumental in promoting open and equitable scholarship to enhance academic research’s transparency and accessibility. In 2020, the ORFG formed the Equity & Open Science Working Group, leading to the launch of the Open & Equitable Model Funding Program in 2021. This…
Amaryllis Mavragani, Wale Ajiboye, Gerard Carot-Sans, Meron Mengistu + 4 more
'Kris Tom' 'Liben Gebremikael' 'Notisha Massaquoi' 'Obidimma Ezezika'] Background Implementation science investigates the processes and factors that influence the successful adoption, implementation, and sustainability of interventions in many settings. Although conventional research places significant emphasis on the…
Georges Czaplicki, Serge Mazeres
Model validation depends on the agreement between the predicted and experimental data. However, finding solutions to problems, described by equations with many parameters, for which virtually nothing is known, is a difficult task. For example, the extraction of kinetic parameters from complex schemes representing the…
Tracey McConnell, Carolyn Blair, Joanne Reid, Geoff Wong
Implementation science has been defined as the scientific study of methods focused on promoting the systematic uptake of research findings into routine practice in order to improve the quality and effectiveness of healthcare services. However, a recent critique of the science has highlighted a research to practice gap…
Menekşe Özçelik
The enhanced recovery after surgery (ERAS) pathway is a perioperative care pathway intended to facilitate early recovery and minimize hospital stays among patients undergoing major surgery. Critical factors for successful ERAS implementation, which may vary depending on care processes, include a multidisciplinary team…
Brian Hie, Salvatore Candido, Zeming Lin, Ori Kabeli + 4 more
Combining a basic set of building blocks into more complex forms is a universal design principle. Most protein designs have proceeded from a manual bottom-up approach using parts created by nature, but top-down design of proteins is fundamentally hard due to biological complexity. We demonstrate how the modularity and…
George Chao, Evan Appleton, Clair S. Gutierrez, Lilia Evgeniou + 4 more
Pluripotent cells specialize into numerous cell types by receiving external signals, making fate decisions, and executing differentiation functions – a paradigm similar to computer algorithms. While advances in biosensor design have enabled cells to respond to diverse stimuli, the ability to maintain a synthetic memory…
Yann Spöri, Jean-François Flot
Haxe is a general purpose, object-oriented programming language supporting syntactic macros. The Haxe compiler is well known for its ability to translate the source code of Haxe programs into the source code of a variety of other programming languages including Java, C++, JavaScript and Python. Although Haxe is…
Patrick D. Brandt, Dawayne Whittington, Kimberley D. Wood, Chris Holmquist + 4 more
A doctoral-level internship program was developed at the University of North Carolina at Chapel Hill with the intent to create customizable experiential learning opportunities for biomedical trainees to support career exploration, preparation, and transition into their post-graduate professional roles. We report the…
Tzuhsuan Ma, Ann M Hermundstad
When foraging in dynamic and uncertain environments, animals can benefit from basing their decisions on smart inferences about hidden properties of the world. Typical theoretical approaches to understand the strategies that animals use in such settings combine Bayesian inference and value iteration to derive optimal…