29 papers · ranked by Valyu relevance
Gaspare Saltarelli, Giovanni Di Cerbo, Antonio Innocenzi, Claudia De Felici + 3 more
Quantitative magnetic resonance imaging (qMRI) denotes MRI methods that estimate physical tissue parameters in units, rather than relative signal. Typical readouts include T1/T2 relaxation (ms; or R1/R2 in s−1), proton density (%), diffusion metrics (e.g., ADC in mm2/s, FA), magnetic susceptibility (χ, ppm), perfusion…
Dvir Radunsky, Chen Solomon, Neta Stern, Tamar Blumenfeld-Katzir + 12 more
'Shir Filo' 'Aviv Mezer' 'Anita Karsa' 'Karin Shmueli' 'Lucas Soustelle' 'Guillaume Duhamel' 'Olivier M. Girard' 'Gal Kepler' 'Shai Shrot' 'Chen Hoffmann' 'Noam Ben-Eliezer' 'Marco Giannelli'] Quantitative MRI (qMRI) has been shown to be clinically useful for numerous applications in the brain and body. The development…
Jaejin Cho, Borjan Gagoski, Tae Hyung Kim, Fuyixue Wang + 8 more
'Daniel Nico Splitthoff' 'Wei‐Ching Lo' 'Wei Liu' 'Daniel Polak' 'Stephen Cauley' 'Kawin Setsompop' 'P. Ellen Grant' 'Berkin Bilgiç'] - 4 Department of Computer Engineering, Hongik University, Seoul, South Korea - 5 Siemens Healthcare GmbH, Erlangen, Germany - 6 Siemens Medical Solutions USA, Inc., Charlestown…
Lingjing Chen, Chengxiu Zhang, Yinqiao Yi, Yida Wang + 8 more
((1) Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai, China, (2) Institute of Magnetic Resonance and Molecular Imaging in Medicine, East China Normal University, Shanghai, China, (3) MR Research Collaboration Team, Siemens Healthineers…
Albert Jang, Kwok‐Shing Chan, Azma Mareyam, Jason Stockmann + 5 more
1## INTRODUCTION Quantitative MRI (qMRI) quantifies MR tissue properties, providing information regarding tissue microstructure and microenvironment. It utilizes tissue models based on spin physics to quantitatively measure a tissue parameter of interest (e.g., tissue relaxation, diffusion, perfusion, susceptibility…
Jelmer van Lune, Niels Kuster, Oscar van der Heide, Matteo Maspero + 4 more
Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic tissue parameters, the requirement for specialized acquisition protocols and…
Susan V. van Hees, Martin B. Schilder, Alexandra Keyser, Alessandro Sbrizzi + 2 more
'Alessandro Sbrizzi' 'Jordi P.D. Kleinloog' 'Wouter P.C. Boon'] Purpose MRI waitlists and discomfort from long scanning sessions are significant problems in clinical radiology. Novel multiparametric quantitative MRI techniques (qMRI) for radiological imaging enable acquisition of full-brain data within minutes to…
Maya Yablonski, Zihan Zhou, Xiaozhi Cao, Sophie Schauman + 3 more
Developmental cognitive neuroscience aims to shed light on evolving relationships between brain structure and cognitive development. To this end, quantitative methods that reliably measure individual differences in brain tissue properties are fundamental. Standard qualitative MRI sequences are influenced by scan…
Agah Karakuzu, Labonny Biswas, Julien Cohen-Adad, Nikola Stikov
We developed an end-to-end workflow that starts with a vendor-neutral acquisition and tested the hypothesis that vendor-neutral sequences decrease inter-vendor variability of T1, MTR and MTsat measurements. We developed and deployed a vendor-neutral 3D spoiled gradient-echo (SPGR) sequence on three clinical scanners by…
Yuya Hirano, Kinya Ishizaka, Hiroyuki Sugimori, Yo Taniguchi + 3 more
'Tomoki Amemiya' 'Yoshitaka Bito' 'Kohsuke Kudo'] We aimed to evaluate the accuracy and repeatability of the T1, T2, and proton density (PD) values obtained by quantitative parameter mapping (QPM) using the ISMRM/NIST MRI system phantom and compared them with computer simulations. We compared the relaxation times and…
Raquel González-Alday, Adriana Ferreiro, Nuria Arias-Ramos, Blanca Lizarbe + 1 more
Magnetic resonance imaging (MRI) is essential in both research and clinical settings, with quantitative MRI (qMRI) enhancing reproducibility and sensitivity. However, qMRI processing can be complex, especially for users with limited coding experience. We introduce Resomapper, an open-source, cross-platform tool that…
Matt G. Hall, Matt Cashmore, Hyo-Min Cho, Bernd Ittermann + 12 more
'Kathryn E. Keenan' 'Christoph Kolbitsch' 'Changwoo Lee' 'Chengwei Li' 'Asante Ntata' 'Katie Obee' 'Zhang Pu' 'Stephen E. Russek' 'Karl F. Stupic' 'Lukas Winter' 'Luca Zilberti' 'Michael Steckner'] Quantitative MRI has been an active area of research for decades and has produced a huge range of approaches with enormous…
Mikhail Zubkov, Kerrin J Pine, Pierre-Louis Bazin, Puneet Talwar + 13 more
Quantitative MRI (qMRI) measures relaxation rates, exchange rates and proton densities that reflect the biophysical properties of tissue and are ideally free from protocol- and scanner-dependence. In practice, qMRI has not yet achieved this level of independence from sequence and hardware choice, and quantitative…
Arjun Desai, Andrew H. Schmidt, Elka Rubin, Christopher M. Sandino + 8 more
'Marianne S. Black' 'Valentina Mazzoli' 'Kathryn J. Stevens' 'Robert D. Boutin' 'Christopher Ré' 'Garry E. Gold' 'Brian A. Hargreaves' 'Akshay Chaudhari'] Magnetic resonance imaging (MRI) is a cornerstone of modern medical imaging. However, long image acquisition times, the need for qualitative expert analysis, and the…
Shizhuo Li, Unay Dorken Gallastegi, Shohei Fujita, Yuting Chen + 7 more
Purpose: To improve the accuracy of multiparametric estimation, including myelin water fraction (MWF) quantification, and reduce scan time in 3D-QALAS by optimizing sequence parameters, using a self-supervised multilayer perceptron network.Methods: We jointly optimize flip angles, T 2 preparation durations, and…
Riyan Mohamed Sajer, Saikiran Pendem, Rajagopal Kadavigere, Priyanka - + 6 more
Introduction Magnetic resonance imaging (MRI) is essential for brain imaging, but conventional methods rely on qualitative contrast, are time-intensive, and prone to variability. Magnetic resonance finger printing (MRF) addresses these limitations by enabling fast, simultaneous mapping of multiple tissue properties…
Nikita Vladimirov, Or Perlman
Immunotherapy constitutes a paradigm shift in cancer treatment. Its FDA approval for several indications has yielded improved prognosis for cases where traditional therapy has shown limited efficiency. However, many patients still fail to benefit from this treatment modality, and the exact mechanisms responsible for…
Padriac Hooper, Jin Jin, Kieran O’Brien, Markus Barth
Quantitative Susceptibility Mapping (QSM) relies on a tissue’s underlying macroscopic geometry to lead to measurable orientation-dependent field perturbations. To understand and assess QSM error in vivo, anthropomorphic phantoms provide a useful model that mimic the electromagnetic properties and morphology of…
Marta Micek, David Aebisher, Justyna Surówka, Dorota Bartusik-Aebisher + 1 more
'Dorota Bartusik-Aebisher' 'Michał Madera'] Introduction The purpose of this review was to summarize current applications of non-contrast-enhanced quantitative magnetic resonance imaging (qMRI) in tissue differentiation, considering healthy tissues as well as comparisons of malignant and benign samples. The analysis…
Naila Rahman, Jordan Ramnarine, Kathy Xu, Arthur Brown + 1 more
Magnetization transfer saturation (MTsat) imaging was developed to reduce T1 dependence and improve specificity to myelin compared to the widely used MT ratio (MTR), while maintaining a feasible scan time. Knowledge of MTsat reproducibility is necessary to apply MTsat in preclinical neuroimaging. To assess the…
Nikita Vladimirov, Moritz Zaiss, Or Perlman
Methods: The Cram´er-Rao bound (CRB) for variance assessment was employed on Bloch-McConnell-based simulated signals, followed by a numerical sequential quadratic programming optimization and basinhopping avoidance of local minima. Validation was performed using L-arginine phantoms and healthy human volunteers (n=4) at…
Leon Y. Cai, Stephanie N. Del Tufo, Laura Barquero, Micah D’Archangel + 8 more
Magnetic resonance spectroscopy (MRS) is one of the few non-invasive imaging modalities capable of making neurochemical and metabolic measurements in vivo. Traditionally, the clinical utility of MRS has been narrow. The most common use has been the “single-voxel spectroscopy” variant to discern the presence of a…
Authors not listed
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and widespread neurovascular disturbances. Traditional fMRI provides valuable spatial maps of blood-oxygen-level-dependent (BOLD) changes but often lacks the capacity to quantify the interplay of cerebral blood flow…
Padriac Hooper, Jin Jin, Kieran O’Brien, Monique Tourell + 2 more
Quantitative susceptibility mapping (QSM) is an MR technique that depicts and precisely quantifies spatial biodistributions from MR phase images. Recently, QSM has gained much uptake as method for mapping iron and identifying calcium. However, QSM as a quantitative method needs an objective reference to assess its…
Authors not listed
When producing plant-protein-based meat analogues via high moisture extrusion (HME), the structure of extrudates is determined by complex interactions between ingredient composition and processing conditions. To facilitate consumers in their transition towards a diet higher in plant-based proteins, the food industry…
Aitang Xing, Gary Goozée, Gary Liney, Sankar Arumugam + 7 more
simulator Authors: ['Aitang Xing' 'Gary Goozée' 'Gary Liney' 'Sankar Arumugam' 'Shrikant Deshpande' 'Anthony Espinoza' 'Alison Gray' 'Vasilis Kondilis' 'Doaa Elwadia' 'Robba Rai' 'Lois Holloway'] Abstract A software system named AutoMRISimQA was developed to monitor the daily performance of a wide-bore 3T scanner (MRI)…
Marc Azagra, David Gomez-Cabeza, Alejandro Portela, Gergo Matajsz + 3 more
To foster the efficient development of 3D cell culture models, we developed a strategy to assess the liquid flow perfusion through biocompatible scaffolds. Biocompatible scaffolds play a crucial role in creating 3D in vitro models for precision medicine. Therefore, it is imperative to thoroughly characterise the…
Authors not listed
Understanding the spatial organization and dynamics of physicochemical processes in operating catalytic reactors is essential for optimizing their performance. Unfortunately, the power of NMR-based techniques is significantly impaired in such studies due to severe broadening and distortions of NMR signals caused by the…
Authors not listed
Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are essential tools in natural and life sciences, but their low sensitivity often hampers their applicability. Photochemically induced dynamic nuclear polarization (photo-CIDNP) offers a versatile and mild method to overcome this limitation. Here, we…