Search · four archives
Search · four archives
6 papers · ranked by Valyu relevance
Abdullah Al Nahid, Linda Serafin, Nicholas Mancuso
In many applications, from statistical inference to machine learning, calculating the trace of a matrix is a fundamental operation, yet may be infeasible due to memory constraints. Stochastic trace estimation offers a practical solution by using randomized matrix-vector products to obtain accurate, unbiased estimates…
Cláudia Brito, Pedro Ferreira, João Paulo
Breakthroughs in sequencing technologies led to an exponential growth of genomic data, providing unprecedented biological in-sights and new therapeutic applications. However, analyzing such large amounts of sensitive data raises key concerns regarding data privacy, specifically when the information is outsourced to…
J Kyle Medley, Shaik Asifullah, Joseph Hellerstein, Herbert M Sauro
Mechanistic kinetic models of biological pathways are an important tool for understanding biological systems. Constructing kinetic models requires fitting the parameters to experimental data. However, parameter fitting on these models is a non–convex, non–linear optimization problem. Many algorithms have been proposed…
Noah Lewis, Harshvardhan Gazula, Sergey M. Plis, Vince D. Calhoun
In this age of big data, large data stores allow researchers to compose robust models that are accurate and informative. In many cases, the data are stored in separate locations requiring data transfer between local sites, which can cause various practical hurdles, such as privacy concerns or heavy network load. This…
Haotian Li
Machine learning and deep learning are novel and trending approaches to solving real-world scientific problems. Graph machine learning is dedicated to performing learning methods, such as graph neural networks, on non-Euclidean data such as graphs. Molecules, with their natural graph structures, could be analyzed by…
Yun William Yu, Griffin M Weber
Researchers use large federated clinical data networks that connect dozens of healthcare organizations to access data on millions of patients. However, because patients often receive care from multiple sites in the network, queries frequently double-count patients. Using the probabilistic streaming algorithm…