14 papers · ranked by Valyu relevance
Bernhard Voelkl, Hanno Würbel
Reproducibility in biomedical research, and more specifically in preclinical animal research, has been seriously questioned. Several cases of spectacular failures to replicate findings published in the primary scientific literature have led to a perceived reproducibility crisis. Diverse threats to reproducibility have…
Erkan Buzbas, Berna Devezer
A core problem that has been addressed in the scientific reform movement so far is the low rates of reproducibility of research results. Mainstream reform literature aimed at increasing reproducibility rates by implementing changes in research practice and scientific policy. At the sidelines of reform, theoreticians…
Erkan O. Buzbas, Berna Devezer, Bert Baumgaertner
The scientific reform movement has proposed openness as a potential remedy to the putative reproducibility or replication crisis. However, the conceptual relationship between openness, replication experiments, and results reproducibility has been obscure. We analyze the logical structure of experiments, define the…
Sheridan Evans, Ian A. Fladie, J. Michael Anderson, Daniel Tritz + 1 more
In recent years, urgency has been placed on the “reproducibility crisis” facing biomedical research. Despite efforts toward improvement, certain elements needed to reproduce a study are often lacking from publications. The current state of reproducibility within the sports medicine research community remains unknown.…
Olavo Bohrer Amaral, Clarissa França Dias Carneiro, Kleber Neves, Ana Paula Wasilewska Sampaio + 209 more
Concerns over the replicability and reproducibility of published research have grown in many research fields, but empirical data to inform policies are still scarce. Biomedical research in Brazil expanded rapidly over the last three decades, with no systematic assessment of the replicability of its findings. With this…
Kelly D. Cobey, Sanam Ebrahimzadeh, Matthew J. Page, Robert T. Thibault + 3 more
We conducted an international cross-sectional survey of biomedical researchers’ perspectives on the reproducibility of research. This study builds on a widely cited 2016 survey on reproducibility, and provides a biomedical-specific and contemporary perspective on reproducibility. To sample the community, we randomly…
Olavo Bohrer Amaral, Clarissa Franca Dias Carneiro, Kleber Neves, Ana Paula Wasilewska Sampaio + 209 more
Concerns over the replicability and reproducibility of published research have grown in many research fields, but empirical data to inform policies are still scarce. Biomedical research in Brazil expanded rapidly over the last three decades, with no systematic assessment of the replicability of its findings. With this…
Joseph Lemaitre, Désirée Popelka, Blandine Ribotta, Hannah Westlake + 8 more
The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a comprehensive assessment, 14 years later, of the replicability of nearly all publications across an entire scientific…
Joseph Lemaitre, Désirée Popelka, Blandine Ribotta, Hannah Westlake + 8 more
The ReproSci project retrospectively analyzed the conceptual replicability of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a comprehensive assessment, 14 years later, of the replicability of nearly all publications across an entire…
Caleb A. Smith, Johnny Nolan, Daniel J. Tritz, Trace E. Heavener + 3 more
Study reproducibility is valuable for validating or refuting results. Provision of reproducibility indicators, such as materials, protocols, and raw data in a study to improve its potential for reproduction. Efforts to reproduce noteworthy studies in the biomedical sciences have resulted in an overwhelming majority of…
Shelby Lynn Rauh, Bradley S. Johnson, Aaron Bowers, Daniel Tritz + 1 more
Many components of transparency and reproducibility are lacking in urology publications, making study replication, at best, difficult. Reproducibility is essential for the integrity of scientific research. Reproducibility is measured by the ability of investigators to replicate the outcomes of an original publication…
Taylor Hughes, Andrew Niemann, Daniel Tritz, Kryston Boyer + 2 more
Previous studies have established a baseline of minimal reproducibility in the social science and biomedical literature. Clinical research is especially deficient in factors of reproducibility. Surgical journals contain fewer clinical trials than non-surgical ones, suggesting that it should be easier to reproduce the…
Jean Peccoud, Derek Johnson, Samuel Peccoud, Julia Setchell + 1 more
Reproducibility is the cornerstone of scientific experiments. Assessing the reproducibility of an experiment requires analyzing the contribution of different factors to the variation of the observed data. Suitable data structures need to be defined prior to the data collection effort so that data associated with these…
Maria Anna Rapsomaniki, Stella Maxouri, Manuel Ramirez Garrastacho, Patroula Nathanailidou + 4 more
DNA replication is a complex and remarkably robust process: despite its inherent uncertainty, manifested through stochastic replication timing at a single-cell level, multiple control mechanisms ensure its accurate and timely completion across a population. Disruptions in these mechanisms lead to DNA re-replication…