22 papers · ranked by Valyu relevance
Guillermo L. Hoffmann, Emily E. K. Kopania, Michael Tene, Amanda Kowalczyk + 5 more
Convergent evolution, or the independent acquisition of similar phenotypes in distinct lineages, provides a powerful framework for investigating genomic changes associated with a phenotype. This paper details an update to RERconverge, a powerful R package that tests for associations between gene relative evolutionary…
Myeongjin Kang, Daejin Park, Luca Di Nunzio, Sergio Spanò
Edge inference systems must sustain real-time performance under dynamic environments such as sensor noise, illumination change, and new object classes. Conventional edge devices deploy static offline-trained models, causing accuracy degradation when the input distribution drifts. This study proposes a runtime-robust…
Elliot Xie, Lingxin Cheng, Yujia Cai, Jack Shireman + 1 more
Performance bottlenecks in widely used genomics and bioinformatics software present a substantial and growing burden as biological datasets continue to increase in size and number. Relieving these bottlenecks relies largely on expert manual optimization and therefore remains difficult to scale. Here we present…
Matthew Leach, Peter Heywood, Alexander G. Fletcher, Paul Richmond
Chaste is an open-source C++ library providing a general-purpose framework for cell-based simulations of biological tissues. It has been applied to a wider range of biological processes, including morphogenesis, carcinogenesis, and wound healing. Such simulations often involve numerous mechanical interactions between…
Hassan Nassar, Rafik Youssef, Lars Bauer, Jörg Henkel
As the need for more computing power grows, traditional methods are hitting limits. To boost performance, we're expanding Central Processing Unit (CPU) capabilities and using specialized hardware accelerators. For example, mobile devices usually have cameras, video encoding, and audio accelerators. To perform the…
Geoffrey X. Yu, Ryan Marcus, Tim Kraska
Relational database management systems (RDBMSes) can process general-purpose queries, but often have lower performance compared to custom-built solutions for specific queries. For example, consider a group-by query over a few known groups (e.g., grouping by country). While an RDBMS would likely use a hash map to do the…
Shuyao Jiang, Ruiying Zeng, Yangfan Zhou, Michael R. Lyu
WebAssembly (Wasm) has emerged as a powerful bytecode format for running applications with near-native performance in portable and secure environments. However, while Wasm currently supports compiled languages like C, C++, and Rust, it lacks robust support for managed languages such as Python, Java, and JavaScript.…
Bojie Li
Hardware accelerators now sit on the critical path of online serving. GPUs, FPGAs, and increasingly remote services such as hardware security modules, post-quantum KEMs, and inference servers. For fine-grained offloads (microseconds to a few milliseconds) the classic responses to the resulting stall both fail: a…
Kenji Gerhardt, Shujun Ou
The rapid expansion of high-quality, nearly complete eukaryotic genomes demands computational accelerations of existing bioinformatic infrastructure. TIR-Learner has been widely used for the de novo identification of Terminal Inverted Repeat (TIR) transposons, but suffers from slow runtime and a large memory footprint.…
Lili Jia, Biyu Zhang, Tseching Liang, Guojie Wang + 2 more
Background Sled sprint training to improve athletes’ sprint performance is becoming increasingly popular. However, there is still no consensus on the appropriate resistance to improve acceleration, and few studies have focused on adolescent sprinters. This study aimed to investigate the effects of 8 weeks of different…
Dylan S. Hicks, Stuart McMillan, Wolfgang Schöllhorn, Roland van den Tillaar
Sprinting is a complex skill required in many team and individual sports, with practitioners placing an emphasis on enhancing this aspect of performance to improve sporting success. The task of sprinting involves patterns of inter- and intra-limb coordination and control, which emerge as the athlete accelerates to…
Shubhabrata Dutta, Purba Bhattacharya, Tanay Dey, Nayana Majumdar + 1 more
Accurate electric field estimation is critical for the design and optimization of Micro Pattern Gaseous Detectors (MPGDs). The nearly exact Boundary Element Method (neBEM) offers high precision field computation but is limited by long CPU runtime arising from its complex analytical formulations. This work presents a…
Megan Dreher, Alexis Terterov, Olivia Feistner, Laura Freiermuth + 3 more
Motivational music has been shown to improve running performance through delaying fatigue and increasing run duration. Previous studies have highlighted the effect of music tempo, that matching tempo to the runner’s cadence delays running fatigue. It remains unclear whether the motivational content in music lyrics is…
Ruiying Zeng, Shuyao Jiang, Wenxuan Zhao, Yangfan Zhou
Performance debugging in WebAssembly (Wasm) runtimes is essential for ensuring the robustness of Wasm, especially since performance issues have frequently occurred in Wasm runtimes, which can significantly degrade the capabilities of hosted services. Many performance issues in Wasm runtimes result from suboptimal…
Mateusz Jopek, Michal Krzysztofik, Dariusz Mroczek, Adam Zajac + 1 more
The study aimed to determine the influence of functional asymmetry on the kinematic parameters of the 50 m run and its significance in shaping maximum speed in sprinters at various sports levels. The analysis included 18 Polish sprinters (elite: ≤ 10.40 s, sub-elite: ≤ 11.10 s per 100 m) who performed four 50 m runs…
Hussein Sharadga, Yuhan Du, Javad Mohammadi
This paper presents an accelerated solver for the unit commitment problem in large-scale power systems. The approach is based on the concurrent execution of GPU- and CPU-based optimization solvers on a single machine, with the solver that converges first terminating the other to minimize overall runtime. This strategy…
Andrew Usher, John Babraj, Adam Younger, Ugo Carraro
Football requires repeated sprint ability for game-changing moments; however, the demand on the skeletal muscles is unknown. The aim of the current study was to determine the muscle oxygen response during duplicate sprints in professional footballers. Eight male professional footballers (age: 29 ± 5 y; height: 181 ± 8…
James A. London, Abhishek K. Singh, Teague C. Svendsen, Naciye Esma Tirtom + 2 more
Magnetic tweezers are a popular biophysical instrument for manipulating and measuring single molecules. Most groups rely on custom-built setups tailored to specific experiments, making it challenging to implement and share software. Typically, image acquisition and hardware control are automated via LabVIEW, while…
Yusufcan Keskin, Mehmet Yavuz Taşkıran, Gürkan Elçi
Purpose The increasing physical demands of modern women’s football necessitate integrated training approaches capable of simultaneously enhancing acceleration, force production, and neuromuscular control. Although devices such as the Exer-Genie® are frequently implemented in resisted sprint training, scientific…
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Bayesian optimization (BO) has become increasingly important for experimental optimization across scientific domains, yet implementing BO pipelines requires significant programming expertise and familiarity with specialized frameworks. This creates a barrier for domain experts who could benefit from BO but lack the…
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A framework for catalysis based on categorical aperture selection rather than temporal acceleration is presented. Traditional catalysis theory describes catalysts as agents that accelerate reactions by lowering activation energies, implicitly treating time as the fundamental variable and reaction rate enhancement as…
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This comprehensive review examines the evolution of autonomous materials synthesis laboratories that integrate artificial intelligence with advanced robotics to accelerate discovery. Traditional materials development pipelines typically require 10-20 years, but self-driving laboratories (SDLs) and Materials…