12 papers · ranked by Valyu relevance
Kai-Chun Lin, Marc Dandin
We report a 0.18 µm CMOS lab-on-a-chip system that monolithically integrates a passive radio frequency identification (RFID) interface and an 8 × 8 array of capacitance sensors configured for measuring the capacitance change resulting from an overlying biological specimen. This lab-on-CMOS platform is designed to…
Nicholas A. Alexander, Alberto Mariola, Sahitya Puvvada, Yulia Bezsudnova + 3 more
Optically pumped magnetometers (OPMs) can be used for magnetoencephalography (MEG) with equivalent or improved signal to noise ratio, relative to cryogenic MEG, when sensors are placed close to the scalp. OPM-based MEG can also be used in mobile contexts if sensors are placed in lightweight, wearable arrays.…
Hisatoshi Mimura, Toshihisa Osaki, Haruka Oda, Sho Takamori + 4 more
Detecting volatile urinary biomarkers offers a compelling strategy for noninvasive diagnosis of diseases such as cancer. Biohybrid sensors employing sensor cells that express olfactory receptors—with finely tuned molecular recognition capabilities—are garnering increasing attention. However, their application to…
Bashar Emon, Ahmadreza Kashefi, Md Habibur Rahman, Darbaz Adnan + 11 more
The tumor microenvironment plays a critical role in drug resistance, with extracellular matrix (ECM) mechanics, cell-cell crosstalk, and transport barriers contributing to poor therapeutic outcomes. Traditional two-dimensional (2D) cultures fail to capture these features, and drug efficacy in 2D often does not…
Ravi Umadi
Accurate spatial localisation of free-flying echolocating bats is foundational for resolving fine-scale flight behaviour, prey interception, and spatial decision-making in natural environments. Acoustic localisation using microphone arrays is widely employed for this purpose, yet array geometries in field studies are…
Oindrila Hossain, Yan Wang, Mingzhuo Li, Sina Jamalzadegan + 4 more
Volatile organic compounds (VOCs) are common constituents of fruits, vegetables, and crops, and are closely associated with their quality attributes, such as firmness, sugar level, ripeness, translucency, and pungency levels. While VOCs are vital for assessing vegetable quality, traditional detection methods, such as…
Michael Rappleye, Adam Gordon-Fennel, Daniel C. Castro, Avi K. Matarasso + 12 more
Fluorescent sensor proteins are instrumental for detecting biological signals in vivo with high temporal accuracy and cell-type specificity. However, engineering sensors with physiological ligand sensitivity and selectivity is difficult because they need to be optimized through individual mutagenesis in vitro to assess…
Zhuolun Meng, Liam White, Pengfei Xie, S. Reza Mahmoodi + 5 more
This work explores label-free biosensing as an effective method for biomolecular analysis, ensuring the preservation of native conformation and biological activity. The focus is on a novel electronic biosensing platform utilizing micro-fabricated nanowell-based impedance sensors, offering rapid, point-of-care diagnosis…
Chidozie Victor Agu, Rebecca L Cook, William Martelly, Lydia R Gushgari + 2 more
An automated proteomic platform for producing and screening an array of functional proteins on biosensor surfaces was developed to address the challenges of measuring proteomic interaction kinetics in high throughput (HTP). This technology is termed Sensor-Integrated Proteome On Chip (SPOC®) which involves in-situ…
Yulu Cai, Caleb Ronders, Vittorio Mottini, Hang Yuan + 11 more
The intelligence of the human biological system is enabled by the highly distributed sensing receptors on soft skin that can distinguish various stimulations or environmental cues, thus establishing the fundamental logic of sensing and physiological regulation or response. To replicate biological perception, two…
Zihan Yin, Md Abdullah-Al Kaiser, Lamine Ousmane Camara, Mark Camarena + 4 more
Neuromorphic image sensors draw inspiration from the biological retina to implement visual computations in electronic hardware. Gain control in phototransduction and temporal differentiation at the first retinal synapse inspired the first generation of neuromorphic sensors, but processing in downstream retinal…
Alison I Weber, Mahnoush Babaei, Amanuel Mamo, Bingni W Brunton + 2 more
Sensory feedback is essential to both animals and robotic systems for achieving coordinated, precise movements. Mechanosensory feedback, which provides information about body deformation and position in space, depends not only on the properties of sensors but also on the structure in which they are embedded. In…