11 papers · ranked by Valyu relevance
Jidong Liu, Jianxiong Xie, Qiaoyan Hao, Yutao Hu + 6 more
Reconfigurable optoelectronic image sensors capable of in-sensor computing are promising for energy-efficient edge visual perception. Self-powered photovoltaic operation further reduces the power demand of image sensing and processing. However, it remains challenging to achieve a continuously gate-tunable self-powered…
Justin D Shin, Michael Satchell, Paul Miller, Shantanu P Jadhav + 2 more
REM (rapid eye movement) and non-REM (NREM) sleep stages contribute to systems memory consolidation in hippocampal-cortical circuits. However, the physiological mechanisms underlying REM memory processes remain relatively unclear compared to NREM memory reactivation. Here we report, in rodents, the existence of…
Hao Ding, Nannan Wu, Tianyi Qiu
DNA foundation models such as Evo2 7B adopt hybrid Hyena/attention architectures (Striped-Hyena2) whose single-stream autoregressive decoding is bounded by weight bandwidth at ∼45 tok/s. Speculative decoding on such hybrids faces a systems problem that prior SSM work solves only partially: after a draft is verified…
Yiming Xue, Xiaojian Liu, Weimin Zhu, Shengfan Wang + 2 more
While protein-RNA interactions are fundamental to post-transcriptional processes, achieving a holistic understanding of their regulatory logic remains challenging. Current computational models often treat binding affinity, interface mapping, and RNA design as isolated tasks, thereby failing to provide a unified…
Emily Cordeiro, Daniela Herrera Chaves, Nima Talei, Iván Castro + 6 more
Statistical learning (SL) has been proposed to depend on the hippocampus, but traditional neuropsychological theories of long-term memory posit that the hippocampus is only necessary for explicit memory processes, not implicit memory processes. To reconcile these two accounts, we exposed 27 temporal lobe epilepsy (TLE)…
Fabio Cumbo, Kabir Dhillon, M. Hassan Najafi, Sercan Aygun + 1 more
The exponential growth of genomic databases necessitates alignment-free methods for comparing genomes. While MinHash-based tools have revolutionized this field by efficiently estimating the Average Nucleotide Identity based on k-mer sets, they inherently discard structural genomic information. We introduce HyperSketch…
Eliezer Masliah
How transient neural representations become integrated and stable enough to function as internal neural models remains incompletely understood. Grounded in efficient coding, Bayesian and predictive frameworks, recurrent and attractor dynamics, neural state-space models, and systems neuroscience, the Principle of…
Jeffrey D. Walker, Paul Aparicio, Shreya Saxena, Nicholas G. Hatsopoulos + 1 more
The ability to record neural populations during natural behavior now allows us to ask whether canonical motor-cortical dynamics, defined largely in constrained reaches to static targets, also organize self-paced, feedback-rich actions that require continuous correction. We recorded sensorimotor cortex in marmosets…
Namasi G Sankar, Georgios Miliotis, Simon Caton
Genome assembly is important in infectious disease surveillance, antimicrobial resistance monitoring, and cancer genomics. The task of reconstructing full genomic sequences from fragmented reads, can be framed as a large scale combinatorial optimisation problem. Recent advances in quantum computing have introduced new…
Hiroyuki Kusano, Takayuki Shiomi
Digital pathology has rapidly expanded over the past decade, driven by advances in whole-slide imaging and increasing demand for remote and data-integrated diagnostic workflows. However, many implementations remain limited to partial digitization, without fundamentally transforming laboratory and diagnostic processes.…
Lou Thomas, Gaia Scerif, Hodo Yusuf, Mackenzie Laird + 3 more
Diffusion decision models (DDMs) offer the potential to go beyond standard accuracy and response-time indices to better understand perceptual decision-making in autism. One unanswered question is whether autistic participants can flexibly adjust the speed and accuracy of their decision-making according to task demands.…