7 papers · ranked by Valyu relevance
Shijie Deng, Brandon Jolly, James Wilkes, Yu Mu + 5 more
Integrated catalysis is an emerging methodology that can streamline the multistep synthesis of complicated products in a single reaction vessel, achieving a high degree of control and reducing the waste and cost of the overall process. Integrated catalysis utilizes spatial and temporal control to couple different…
Gaurav Bahuguna, Fernando Patolsky
Electrochemical reactions are the unrivaled backbone of next generation energy storage, energy conversion and healthcare devices. However, the in-situ real-time visualization of electrochemical reactions, which can shed light on various critical unknown insights on the electrochemical processes, still remains the…
Authors not listed
Sequence is the critical determinant of macromolecular function, yet current polymer design approaches often optimize monomer composition and ratios while ignoring sequence. This creates poorly defined design spaces for active learning that miss the vast combinatorial landscape of sequence possibilities. We introduce…
Elisa Frezza, Damien Laage, Elise Duboué-Dijon
Water molecules are essential to determine the structure of nucleic acids and mediate their interactions with other biomolecules. Here, we characterize the hydration dynamics of analogous DNA and RNA double helices with unprecedented resolution and elucidate the molecular origin of their differences: localization of…
Neetu ., Aman Saini, Rishi Ram Mahato, Priyanka . + 1 more
The theory behind origin of life to Darwinian evolution considers emergence of dissipative structures driven by the flow of energy across all length scales. To this end, developing and deeper understanding of non-equilibrium self-assembly processes under continuous supply of energy is a demanding matter, both in…
Cindy Ng, Anirban Samanta, Ole Aalund Mandrup, Emily Tsang + 3 more
The folding of double-stranded DNA around histones is a central mechanism in eukaryotic cells for compacting the genetic information into chromosomes. Very few artificial methods are available for controlling the shape of dsDNA at any level, whereas several artificial methods have been developed to efficiently organize…
Authors not listed
Terminally labeled DNA oligonucleotides have wide applications in modern biology and biotechnological applications. It has been observed that the fluorescent intensity of light released from these fluorescent labels is heavily influenced by the terminal sequence of nucleotides. Recent studies have assayed and published…