Search · four archives
Search · four archives
13 papers · ranked by Valyu relevance
Sarah A. Gagliano, Reena Ravji, Michael R. Barnes, Michael E. Weale + 1 more
Although technology has triumphed in facilitating routine genome re-sequencing, new challenges have been created for the data analyst. Genome scale surveys of human disease variation generate volumes of data that far exceed capabilities for laboratory characterization, and importantly also create a substantial burden…
Nastasiya F. Grinberg, Ross D. King
In phenotype prediction the physical character of an organism is predicted from knowledge of its genotype and environment. Such studies are of the highest societal importance as they are now of central importance to medicine, crop-breeding, etc. We investigated two phenotype prediction problems: one simple and clean…
Almas Jabeen, Nadeem Ahmad, Khalid Raza
RNA-Seq measures expression levels of several transcripts simultaneously. The identified reads can be gene, exon, or other region of interest. Various computational tools have been developed for studying pathogen or virus from RNA-Seq data by classifying them according to the attributes in several predefined classes…
Joram Soch, Carsten Allefeld
We propose the statistical modelling approach to supervised learning (i.e. predicting labels from features) as an alternative to algorithmic machine learning (ML). The approach is demonstrated by employing a multivariate general linear model (MGLM) describing the effects of labels on features, possibly accounting for…
Joshua P. Jahner, C. Alex Buerkle, Dustin G. Gannon, Eliza M. Grames + 11 more
The proliferation of biological data with large numbers of samples and many dimensions is kindling hope that life scientists will be able to fit statistical and machine learning models that are highly predictive and interpretable. However, large biological data sets are commonly burdened with an inherent trade-off…
Shreeya Banerji
Diabetes mellitus is a growing problem, especially in developing countries. People suffering from diabetes have an increased risk of developing a number of serious health problems. Consistently high blood glucose levels can lead to serious diseases affecting the heart and blood vessels, eyes, kidney, etc. In addition…
Aryan Yazdanpanah, Michael Chong Wang, Ethan Trepka, Marissa Benz + 1 more
Natural environments are abundant with patterns and regularities. These regularities can be captured through statistical learning, which strongly influences perception, memory, and other cognitive functions. By combining a sequence-prediction task with an orthogonal multidimensional reward learning task, we tested…
M. Zanin, D. Papo, P. A. Sousa, E. Menasalvas + 3 more
The increasing power of computer technology does not dispense with the need to extract meaningful in-formation out of data sets of ever growing size, and indeed typically exacerbates the complexity of this task. To tackle this general problem, two methods have emerged, at chronologically different times, that are now…
Joshua J. Levy, A. James O’Malley
Machine learning approaches have become increasingly popular modeling techniques, relying on data-driven heuristics to arrive at its solutions. Recent comparisons between these algorithms and traditional statistical modeling techniques have largely ignored the superiority gained by the former approaches due to…
Kaushal Kumar, Vijay Vikram Singh, Ramakrishna Ramaswamy
Machine learning (ML) plays a key job in the guide of cancer diagnosis and identification. The researcher has implemented different algorithms of ML for the prediction of breast cancer. Some researchers recommend their algorithms are more accurate, faster, and easier than others. My study relies on recently developed…
Matthew J. K. Vince, Kristin A. Hughes, Anastasiya Buzuk, Deborah L. Perlstein + 2 more
Machine learning (ML) is rapidly gaining traction in many areas of experimental molecular science for elucidating relationships and patterns in large or complex data sets. Historically, ML was largely the preserve of those with specialized training in fields such as statistics or cheminformatics. Increasingly, however…
Husam Abdulnabi, J. Timothy Westwood
A quantitative measurement can have variation, referred to here as measurement variation, which is a probability distribution. Machine Learning models typically produce a prediction corresponding to the mode of the measurement variation. The Deviation Error is a novel metric, described here, to assess predictions that…
Danilo Bzdok, Denis Engemann, Olivier Grisel, Gaël Varoquaux + 1 more
In the 20^th^ century many advances in biological knowledge and evidence-based medicine were supported by p-values and accompanying methods. In the beginning 21^st^ century, ambitions towards precision medicine put a premium on detailed predictions for single individuals. The shift causes tension between traditional…