7 papers · ranked by Valyu relevance
Md Shafayet Hossain, Yi-Ping Phoebe Chen
Non-coding RNAs (ncRNAs), once considered genomic dark matter, are now established as key regulators of gene expression with widespread roles in cellular homeostasis and disease. In cancer, ncRNA expression is frequently and systematically dysregulated, and many of these molecules circulate in stable, protected form…
Maria B. Walter Costa, Rose Brouns, Maria Schreiber, Aristeidis Litos + 5 more
Understanding the adaptations of microorganisms to their environment is key to predicting the stability and dynamics of microbial communities. To uncover molecular mechanisms of environmental response, we extracted genomic features from 13,554 prokaryotic isolates, and trained machine learning models to identify which…
Nazanin Zahra Keshvari, Sara Asl Motaleb Nejad Sarkhab, Tara Shahmoradi, Mohammad Pourashory + 3 more
5.1### Limitations of Biomarkers in Traditional Diagnosis of MDD Standard diagnosis of MDD is only reliable clinically through history taking and psychiatric evaluation. This approach is susceptible to false positives and false negatives in diagnosis. Additionally, precision medicine in MDD pharmacotherapy has not been…
Mathias Claeys, Neil Fam, Xiaojiao Xiao, Tejas Vyas + 10 more
Background Patient selection for transcatheter mitral valve edge-to-edge repair (MTEER) remains challenging, particularly in individuals with complex mitral valve anatomy. Conventional risk scores incorporate limited clinical variables and do not adequately account for detailed echocardiographic features, resulting in…
Ye Gao, Ni Wang, Zhaoyang Xiao, Alessandro Medoro
To further refine the candidate genes and identify robust feature genes, the glmnet package (v4.1.4) was used to perform 10-fold cross-validation least absolute shrinkage and selection operator (LASSO) regression analysis. Genes with non-zero coefficients in the optimal model (lowest mean squared error) were retained…
Yu Zhang, Hui Wang, Liping Zhang
Neonatal hyperbilirubinemia is common in early neonatal life, and delayed recognition of high-risk infants may result in bilirubin-induced neurological injury. Prediction models based on routinely available maternal, perinatal, neonatal, and standardized laboratory variables may support early risk stratification as an…
Konrad Karlsson
Individual encounter histories are central to capture–recapture models, but fisheries monitoring is often reduced to counts that do not account for variation in detection probability. This study presents a machine-vision workflow for converting long-term video surveillance of Atlantic salmon (Salmo salar) and sea trout…