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Search · four archives
13 papers · ranked by Valyu relevance
Philippe Karan, Alexis Reymbaut, Guillaume Gilbert, Maxime Descoteaux
Diffusion tensor imaging (DTI) is widely used to extract valuable tissue measurements and white matter (WM) fiber orientations, even though its lack of specificity is now well-known, especially for WM fiber crossings. Models such as constrained spherical deconvolution (CSD) take advantage of high angular resolution…
Filip Szczepankiewicz, Malwina Molendowska, Samo Lasič, Marcella E Safi + 7 more
Tensor-valued diffusion encoding employs gradient waveforms that enable unique sensitivity to microstructural features of tissue, but the interpretation of signal and parameters may be confounded by diffusion-time dependence. We introduce a framework for restriction-weighted q-space trajectory imaging (ResQ) that…
Maxime Yon, Omar Narvaez, Jan Martin, Hong Jiang + 5 more
Time- or frequency-dependent (“restricted”) diffusion potentially provides useful information about cellular-scale structures in the brain but is challenging to interpret because of the intravoxel tissue heterogeneity. Frequency-dependence was recently incorporated in a multidimensional diffusion-relaxation correlation…
Yiang Pan, Yuanjing Feng, Jianzhong He, William Consagra + 3 more
Diffusion MRI (dMRI) enables noninvasive characterization of white-matter fiber orientations and tissue microstructure, but widely used approaches, such as constrained spherical deconvolution (CSD) and parametric multicompartment models, typically address these features separately. The diffusion tensor distribution…
Maxime Yon, Omar Narvaez, Daniel Topgaard, Alejandra Sierra
Massively Multidimensional Diffusion MRI combines tensor-valued encoding, oscillating gradients, and diffusion-relaxation correlation to provide multicomponent sub-voxel parameters depicting the tissue microstructure. This method was successfully implemented ex vivo in micro-imaging systems and in clinical conditions…
Alexandru V. Avram, Kadharbatcha S. Saleem, Peter J. Basser
Diffusion MRI studies with resolutions of a few hundred micrometers have consistently shown that in the cortex water diffusion occurs preferentially along radial and tangential orientations with respect to the cortical surface, in agreement with histology. These dominant orientations do not change significantly even if…
Maryam Afzali, Santiago Aja-Fernández, Derek K Jones
It has been shown previously that for a very specific form of diffusion-encoding, i.e., the conventional Stejskal-Tanner pulsed gradient, or ‘linear tensor encoding’ (LTE), and in tissue in which diffusion exhibits a ‘stick-like’ geometry, the diffusion-weighted MRI signal at extremely high b-values follows a power…
Kulam Najmudeen Magdoom, Sinisa Pajevic, Gasbarra Dario, Peter J. Basser
The ability to characterize heterogeneous and anisotropic water diffusion processes within macro-scopic MRI voxels non-invasively and in vivo is a desideratum in biology, neuroscience, and medicine. While an MRI voxel may contain approximately a microliter of tissue, our goal is to examine intravoxel diffusion…
Mingyao Liang, Jiangyu Yuan, Chaogang Tang, Pingfu Wang + 7 more
Tensor-valued diffusion MRI (dMRI) enables the separation of total kurtosis into isotropic and anisotropic components, offering improved specificity over conventional Diffusion Kurtosis Imaging (DKI). In this study, we introduce a novel framework for detecting anisotropic-isotropic kurtosis mismatch and evaluate its…
Kulam Najmudeen Magdoom, Alexandru V. Avram, Joelle E. Sarlls, Gasbarra Dario + 1 more
Neural tissue microstructure plays an important role in developmental, physiological and pathophysiological processes. Diffusion tensor distribution (DTD) MRI helps probe heterogeneity at the mesoscopic length scale, orders of magnitude smaller than the nominal MRI voxel size, by describing water diffusion within a…
Maryam Afzali, Sam Coveney, Lars Mueller, Sarah Jones + 7 more
Diffusion tensor imaging (DTI) is commonly used in cardiac diffusion magnetic resonance imaging (dMRI). However, the tissue’s microstructure (cells, membranes, etc.) restricts the movement of the water molecules, making the spin displacements deviate from Gaussian behaviour. This effect may be observed with diffusion…
Rafael Neto Henriques, Marta Correa, Maurizio Maralle, Elizabeth Huber + 5 more
Diffusion-weighted magnetic resonance imaging (dMRI) measurements and models provide information about brain connectivity and are sensitive to the physical properties of tissue microstructure. Diffusional Kurtosis Imaging (DKI) quantifies the degree of non-Gaussian diffusion in biological tissue from dMRI. These…
Uzair Hussain, Ali R. Khan
Diffusion MRI (dMRI) is an imaging technique widely used in neuroimaging research, where the signal carries directional information of underlying neuronal fibres, based on the diffusivity of water molecules. One of the shortcomings of dMRI is that numerous images, sampled at gradient directions on a sphere, must be…