13 papers · ranked by Valyu relevance
Amy M. Ni, Chengcheng Huang, Brent Doiron, Marlene R. Cohen
Increases in perceptual performance correspond to decreases in the correlated variability of sensory neuron responses. No sensory information decoding mechanism has yet explained this relationship. We hypothesize that when observers must respond to a stimulus change of any magnitude, decoders prioritize generality: a…
R. Jabakhanji, A.D. Vigotsky, J. Bielefeld, L. Huang + 3 more
High-profile studies claim to assess mental states across individuals using multi-voxel decoders of brain activity. The fixed, fine-grained, multi-voxel patterns in these “optimized” decoders are purportedly necessary for discriminating between, and accurately identifying, mental states. Here, we present compelling…
Hong-Yun Ou, Takahiro Hasegawa, Osamu Fukayama, Eizo Miyashita
Brain–machine interfaces (BMIs) aim to decode motor intentions from neural activity to enable direct control of external devices. However, most existing decoders rely on monolithic architectures that fail to capture the distinct neural representations of different joint movement directions, limiting their…
Brianna M. Karpowicz, Joel Ye, Chaofei Fan, Pablo Tostado-Marcos + 18 more
Intracortical brain-computer interfaces (iBCIs) can restore movement and communication abilities to individuals with paralysis by decoding their intended behavior from neural activity recorded with an implanted device. While this activity yields high-performance decoding over short timescales, neural data are often…
Jingcheng Zhang, Lei Chen, Jinlin Sun, Shumin Li + 5 more
DNA has emerged as a compelling archival storage medium, offering unprecedented information density and millennia-scale durability. Despite its promise, DNA-based data storage faces critical challenges due to error-prone processes during DNA synthesis, storage, and sequencing. In this study, we introduce Gungnir, a…
Jingxiang Shen, Feng Liu, Chao Tang
Despite fluctuations in embryo size within a species, the spatial gene expression pattern and hence the embryonic structure develop in proportion with embryo size, known as the scaling phenomenon. For morphogen induced patterning of gene expression, the positional information encoded in the morphogen profile is decoded…
Caroline Haimerl, Cristina Savin, Eero P. Simoncelli
Sensory-guided behavior requires reliable encoding of information (from stimuli to neural responses) and flexible decoding (from neural responses to behavior). In typical decision tasks, a small subset of cells within a large population encode task-relevant stimulus information and need to be identified by later…
John-Antonio Argyriadis, Yang-Hui He, Vishnu Jejjala, Djordje Minic
We study the dynamics of genetic code evolution. The algorithm of Vetsigian et al. [1] provides a solution that is both optimal and universal. We reproduce and analyze the algorithm as a dynamical system. All the parameters used in the model are varied to assess their impact on achieving universality. We show that by…
Diego Vidaurre, Radoslaw M. Cichy, Mark W. Woolrich
Brain decoding can predict visual perception from non-invasive electrophysiological data by combining information across multiple channels. However, decoding methods typically confound together the multi-faceted and distributed neural processes underlying perception, so it is unclear what specific aspects of the neural…
Zicong He, Jiajun Zheng, Junwei Duan, Zhe Jin + 6 more
Neural decoding is useful for understanding brain functions and developing neural interface applications. However, neural interfaces based on rigid electronics often suffer from recording instability due to the foreign body responses caused by their mechanical mismatch with soft tissues, limiting the longitudinal…
Kevin D. Volkel, Paul W. Hook, Albert Keung, Winston Timp + 1 more
As nanopore technology reaches ever higher throughput and accuracy, it becomes an increasingly viable candidate for reading out DNA data storage. Nanopore sequencing offers considerable flexibility by allowing long reads, real-time signal analysis, and the ability to read both DNA and RNA. We need flexible and…
Roland Wittler
To index or compare sequences efficiently, often k-mers, i.e., substrings of fixed length k, are used. For efficient indexing or storage, k-mers are often encoded as integers, e.g., applying some bijective mapping between all possible σ^k^ k-mers and the interval [0, σ^k^ −1], where σ is the alphabet size. In many…
Paweł Błażej, Dariusz R. Kowalski, Dorota Mackiewicz, Małgorzata Wnetrzak + 2 more
The standard genetic code (SGC) is the set of rules by which genetic information is translated into proteins, from codons, i.e. triplets of nucleotides, to amino acids. The questions about the origin and the main factor responsible for the present structure of the code are still under a hot debate. Various…